Role of genetic variants and host polymorphisms on COVID‐19: From viral entrance mechanisms to immunological reactions

A Adli, M Rahimi, R Khodaie… - Journal of Medical …, 2022 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), caused by a highly pathogenic emerging
virus, is called severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Knowledge …

A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

A Verma, NL Tsao, LO Thomann, YL Ho… - PLoS …, 2022 - journals.plos.org
The study aims to determine the shared genetic architecture between COVID-19 severity
with existing medical conditions using electronic health record (EHR) data. We conducted a …

LY6E protects mice from pathogenic effects of murine coronavirus and SARS-CoV-2

KB Mar, MC Van Dyke, AH Lopez, JL Eitson, W Fan… - bioRxiv, 2023 - biorxiv.org
LY6E is an antiviral protein that inhibits coronavirus entry. Its expression in immune cells
allows mice to control murine coronavirus infection. However, it is not known which immune …