Vascular endothelial growth factor (VEGF) receptor 3 (VEGFR3), a receptor tyrosine kinase
encoded by the FLT4 gene, plays a significant role in the morphogenesis and maintenance …

The lymphatic vasculature provides an essential route to drain fluid, macromolecules, and
immune cells from the interstitium as lymph, returning it to the bloodstream where the …

Background Conventional advice to reduce the risk of breast cancer-related lymphedema
(BCLE) suggests avoidance of daily-living risks, and limited research has investigated these …

Extensive research supports an evidence-base for cancer treatment-related risk factors,
including extent of lymph node dissection and use of radiotherapy, as contributing to …

Despite a growing body of evidence, current literature demonstrates a persistent gap in the
number of known genes responsible for lymphatic disease entities. Recent clinical …

Lipoedema is a painful non-pitting diffuse “fatty” swelling, usually confined to the legs, that
occurs mainly in women. This scoping review aimed to provide an overview of the available …

Lipedema is a chronic medical condition characterized by a symmetric buildup of adipose
tissue (fat) in the legs and arms. A common but under-recognized disorder, Lipedema may …

Non-cancer-related risk factors for secondary lymphedema were defined across four
categories: co-morbidity, social determinants of health, behavioral factors, and …

Commentary on: Aday et al. National survey of patient symptoms and therapies among 707
women with a lipedema phenotype in the United States. Vasc Med 2024; 29: 36–41; and …

Background: Modified radical mastectomy (MRM) is an excellent surgical approach for
breast cancer. Some complications following mastectomy are wound infection, lymphedema …