[HTML][HTML] Nanotechnology approaches for global infectious diseases
Infectious diseases are a major driver of morbidity and mortality globally. Treatment of
malaria, tuberculosis and human immunodeficiency virus infection are particularly …
malaria, tuberculosis and human immunodeficiency virus infection are particularly …
Physiology and pathophysiology of human airway mucus
The mucus clearance system is the dominant mechanical host defense system of the human
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …
lung. Mucus is cleared from the lung by cilia and airflow, including both two-phase gas-liquid …
Non-invasive delivery strategies for biologics
AC Anselmo, Y Gokarn, S Mitragotri - Nature Reviews Drug Discovery, 2019 - nature.com
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …
clinical and commercial success, biologics are a rapidly growing class and have become a …
[HTML][HTML] Silica nanoparticles: A review of their safety and current strategies to overcome biological barriers
Silica nanoparticles (SNP) have gained tremendous attention in the recent decades. They
have been used in many different biomedical fields including diagnosis, biosensing and …
have been used in many different biomedical fields including diagnosis, biosensing and …
[HTML][HTML] High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance
A Kumar, K Sundaram, J Mu, GW Dryden… - Nature …, 2021 - nature.com
High-fat diet (HFD) decreases insulin sensitivity. How high-fat diet causes insulin resistance
is largely unknown. Here, we show that lean mice become insulin resistant after being …
is largely unknown. Here, we show that lean mice become insulin resistant after being …
Surface modification of lipid-based nanoparticles
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …
purposes, including the recent increase of these nanocarriers as vaccine components …
[HTML][HTML] Micro-and nanoplastics–current state of knowledge with the focus on oral uptake and toxicity
MB Paul, V Stock, J Cara-Carmona, E Lisicki… - Nanoscale …, 2020 - pubs.rsc.org
The production and use of plastics has constantly increased over the last 30 years. Over one
third of the plastics is used in disposables, which are discarded within three years of their …
third of the plastics is used in disposables, which are discarded within three years of their …
Recent advances in mucoadhesive interface materials, mucoadhesion characterization, and technologies
IS Bayer - Advanced Materials Interfaces, 2022 - Wiley Online Library
Mucoadhesion is an extremely important field of adhesion science and the comprehensive
understanding and modulation of mucoadhesion can lead to lifesaving materials and …
understanding and modulation of mucoadhesion can lead to lifesaving materials and …
[HTML][HTML] Mucus interaction to improve gastrointestinal retention and pharmacokinetics of orally administered nano-drug delivery systems
DA Subramanian, R Langer, G Traverso - Journal of nanobiotechnology, 2022 - Springer
Oral delivery of therapeutics is the preferred route of administration due to ease of
administration which is associated with greater patient medication adherence. One major …
administration which is associated with greater patient medication adherence. One major …
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …
commonly used approach for improving the efficiency of drug and gene delivery to target …