Polymeric nanomedicine is a promising and rapidly evolving field. Among the different
polymeric carriers, polymeric micelle (PM) with nanoscale size exhibit potent physical and …

A major limitation in the treatment of cancer patients is the ability of cancer cells to become
resistant to chemotherapeutic drugs, a phenomenon known as multidrug resistance (MDR) …

Novel dispirooxindole-pyrrolidine derivatives have been synthesized through 1, 3-dipolar
cycloaddition of an azomethine ylide generated from isatin and sarcosine with the …

The objective of these studies was to develop Cremophor-free lipid-based paclitaxel (PX)
nanoparticle formulations prepared from warm microemulsion precursors. To identify and …

Cycloviolacin O2 is a small cyclic cysteine‐rich protein belonging to the group of plant
proteins called cyclotides. This cyclotide has been previously shown to exert cytotoxic …

The macromonomer method was used to prepare cross-linked, paclitaxel-loaded polylactide
(PLA)–polyethylene glycol (stealth) nanoparticles using free-radical dispersion …

A new formulation of water‐soluble paclitaxel (P accal® V et) has been developed for
canine cancer patients, without the need for pre‐medication (traditionally required in non …

Introduction: All-trans retinoic acid (ATRA, tretinoin) is the main drug used in the treatment of
acute promyelocytic leukemia (APL). Despite its impressive activity against APL, the same …

Novel series of ()‐catechin derivatives 1a‐l were synthesized, characterized and assayed
for their cytotoxicity against four selected human cancer cell lines by standard MTT assay …

Background Stellera chamaejasme L, a traditional Chinese herb, has long been used for
treatment of various tumors in the Chinese population. In our previous study, we paid an …