Over the past 10 years, the interest in intranasal drug delivery in pharmaceutical R&D has
increased. This review article summarises information on intranasal administration for local …

While behavioral interventions remain the mainstay of treatment of autism spectrum disorder
(ASD), several potential targeted treatments addressing the underlying neurophysiology of …

Background Experimental studies and small clinical trials have suggested that treatment
with intranasal oxytocin may reduce social impairment in persons with autism spectrum …

The acute or chronic drug treatments for different neurodegenerative and psychiatric
disorders are challenging from several aspects. The low bioavailability and limited brain …

Abstract Autism Spectrum Disorder (ASD) refers to a group of neurodevelopmental disorders
including autism, Asperger's syndrome (AS) and pervasive developmental disorder-not …

Background: New research suggests that, rather than representing a core feature of autism
spectrum disorder (ASD), emotional processing difficulties reflect co-occurring alexithymia …

Abstract Purpose of Review Neurodevelopmental disorders disproportionately affect males.
The mechanisms underlying male vulnerability or female protection are not known and …

Oxytocin is a nonapeptide that also serves as a neuromodulator in the human central
nervous system. Over the last decade, a sizeable body of literature has examined its effects …

The blood–brain barrier (BBB) restricts the transport of potential therapeutic moieties to the
brain. Direct targeting the brain via olfactory and trigeminal neural pathways by passing the …

Human emotion recognition is a key technique in human–computer interaction. Traditional
emotion recognition algorithms rely on external actions such as facial expression, which …