Small dense low‐density lipoprotein as biomarker for atherosclerotic diseases

EA Ivanova, VA Myasoedova… - Oxidative medicine …, 2017 - Wiley Online Library
Low‐density lipoprotein (LDL) plays a key role in the development and progression of
atherosclerosis and cardiovascular disease. LDL consists of several subclasses of particles …

Lysophosphatidic acid in atherosclerotic diseases

A Schober, W Siess - British journal of pharmacology, 2012 - Wiley Online Library
Lysophosphatidic acid (LPA) is a potent bioactive phospholipid. As many other biological
active lipids, LPA is an autacoid: it is formed locally on demand, and it acts locally near its …

The phytoestrogen equol increases nitric oxide availability by inhibiting superoxide production: an antioxidant mechanism for cell-mediated LDL modification

J Hwang, J Wang, P Morazzoni, HN Hodis… - Free Radical Biology …, 2003 - Elsevier
Estrogen replacement therapy (ERT) is reported to lower the incidence of cardiovascular
disease in postmenopausal women. ERT also lowers the levels of oxidatively modified low …

Electronegative low-density lipoprotein

JL Sánchez-Quesada, S Benítez… - Current opinion in …, 2004 - journals.lww.com
Recent findings suggest that LDL (-) could contribute to atherogenesis via several
mechanisms, including proinflammatory, proapoptotic and antiangiogenesis properties …

[HTML][HTML] Circulating lipoprotein-carried miRNome analysis reveals novel VLDL-enriched microRNAs that strongly correlate with the HDL-microRNA profile

G Rossi-Herring, T Belmonte, A Rivas-Urbina… - Biomedicine & …, 2023 - Elsevier
Lipoproteins have been described as microRNAs (miRNAs) carriers. Unfortunately, the
bibliography on this topic is scarce and shows a high variability between independent …

[HTML][HTML] Electronegative low-density lipoprotein: origin and impact on health and disease

APQ Mello, IT da Silva, DSP Abdalla, NRT Damasceno - Atherosclerosis, 2011 - Elsevier
Oxidative modifications in lipoproteins (LP), especially in low-density lipoproteins (LDL), are
associated with initiation and progression of atherosclerosis. The levels of a sub-fraction of …

Platelet-activating factor acetylhydrolase is mainly associated with electronegative low-density lipoprotein subfraction

S Benítez, JL Sánchez-Quesada, V Ribas, O Jorba… - Circulation, 2003 - Am Heart Assoc
Background—Electronegative LDL [LDL (−)], a modified subfraction of LDL present in
plasma, induces the release of interleukin-8 and monocyte chemotactic protein-1 from …

Inflammatory biomarkers in type 2 diabetic patients: effect of glycemic control and impact of LDL subfraction phenotype

I Vinagre, JL Sánchez-Quesada… - Cardiovascular …, 2014 - Springer
Background Type 2 diabetes mellitus (T2D) is associated with higher cardiovascular risk
partly related to an increase in inflammatory parameters. The aim of this study was to …

L5-LDL from ST-elevation myocardial infarction patients induces IL-1β production via LOX-1 and NLRP3 inflammasome activation in macrophages

TC Yang, PY Chang, SC Lu - American Journal of …, 2017 - journals.physiology.org
L5-LDL, the most electronegative LDL associated with major cardiovascular risks,
significantly rises in patients with ST-segment elevation myocardial infarction (STEMI). The …

Electronegative LDL of FH subjects: chemical characterization and induction of chemokine release from human endothelial cells

JL Sánchez-Quesada, M Camacho, R Antón, S Benı́tez… - Atherosclerosis, 2003 - Elsevier
Electronegative LDL (LDL (−)) constitutes a plasma subfraction of LDL with proinflammatory
properties. Its proportion is increased in familial hypercholesterolemia (FH); however, the …