Hepatitis D virus infection
T Asselah, M Rizzetto - New England Journal of Medicine, 2023 - Mass Medical Soc
Hepatitis D Virus Infection | New England Journal of Medicine Skip to main content The New
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[HTML][HTML] JAK1 promotes HDV replication and is a potential target for antiviral therapy
MJ Heuschkel, C Bach, L Meiss-Heydmann… - Journal of …, 2024 - Elsevier
Background & Aims Chronic co-infection with HBV and HDV leads to the most aggressive
form of chronic viral hepatitis. To date, no treatment induces efficient viral clearance, and a …
form of chronic viral hepatitis. To date, no treatment induces efficient viral clearance, and a …
Comparative analysis of human, rodent and snake deltavirus replication
P Khalfi, Z Denis, J McKellar, G Merolla… - PLoS …, 2024 - journals.plos.org
The recent discovery of Hepatitis D (HDV)-like viruses across a wide range of taxa led to the
establishment of the Kolmioviridae family. Recent studies suggest that kolmiovirids can be …
establishment of the Kolmioviridae family. Recent studies suggest that kolmiovirids can be …
Hepatitis D virus infection, innate immune response and antiviral treatments in stem cell‐derived hepatocytes
F Lange, J Garn, HA Anagho, FWR Vondran… - Liver …, 2023 - Wiley Online Library
Background Human pluripotent stem cell (hPSC)‐derived hepatocyte‐like cells (HLCs) are a
valuable model to investigate host‐pathogen interactions of hepatitis viruses in a mature …
valuable model to investigate host‐pathogen interactions of hepatitis viruses in a mature …
HepG2BD: A novel and versatile cell line with inducible HDV replication and constitutive HBV expression
M Blanchet, L Angelo, Y Tétreault, M Khabir, C Sureau… - Viruses, 2024 - mdpi.com
Individuals chronically infected with hepatitis B virus (HBV) and hepatitis Delta virus (HDV)
present an increased risk of developing cirrhosis and hepatocellular carcinoma in …
present an increased risk of developing cirrhosis and hepatocellular carcinoma in …
Cellular factors involved in the hepatitis D virus life cycle
K Thiyagarajah, M Basic, E Hildt - Viruses, 2023 - mdpi.com
Hepatitis D virus (HDV) is a defective RNA virus with a negative-strand RNA genome
encompassing less than 1700 nucleotides. The HDV genome encodes only for one protein …
encompassing less than 1700 nucleotides. The HDV genome encodes only for one protein …
[HTML][HTML] Blocking viral entry with bulevirtide reduces the number of HDV-infected hepatocytes in human liver biopsies
L Allweiss, A Volmari, V Suri, JJ Wallin, JF Flaherty… - Journal of …, 2024 - Elsevier
Background & Aims Bulevirtide (BLV) is a first-in-class entry inhibitor and the only approved
treatment for patients chronically infected with HDV in Europe. We aimed to investigate the …
treatment for patients chronically infected with HDV in Europe. We aimed to investigate the …
Hepatitis Delta Virus and Hepatocellular Carcinoma
D Lombardo, MS Franzè, G Caminiti, T Pollicino - Pathogens, 2024 - mdpi.com
The hepatitis D virus (HDV) is a compact, enveloped, circular RNA virus that relies on
hepatitis B virus (HBV) envelope proteins to initiate a primary infection in hepatocytes …
hepatitis B virus (HBV) envelope proteins to initiate a primary infection in hepatocytes …
[HTML][HTML] CAM-A-dependent HBV core aggregation induces apoptosis through ANXA1
V Taverniti, L Meiss-Heydmann, C Gadenne… - JHEP Reports, 2024 - Elsevier
Background & aims Chronic HBV infection is the leading cause of liver disease and
hepatocellular carcinoma. The improvement of antiviral therapies remains an unmet medical …
hepatocellular carcinoma. The improvement of antiviral therapies remains an unmet medical …