COVID-19 and the chemical senses: supporting players take center stage

KW Cooper, DH Brann, MC Farruggia, S Bhutani… - Neuron, 2020 - cell.com
The main neurological manifestation of COVID-19 is loss of smell or taste. The high
incidence of smell loss without significant rhinorrhea or nasal congestion suggests that …

International consensus statement on allergy and rhinology: olfaction

ZM Patel, EH Holbrook, JH Turner… - International forum of …, 2022 - Wiley Online Library
Background The literature regarding clinical olfaction, olfactory loss, and olfactory
dysfunction has expanded rapidly over the past two decades, with an exponential rise in the …

Severe acute respiratory syndrome coronavirus 2 infection reaches the human nervous system: How?

VN Uversky, F Elrashdy, A Aljadawi… - Journal of …, 2021 - Wiley Online Library
Without protective and/or therapeutic agents the severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) infection known as coronavirus disease 2019 is quickly …

Recent developments and highlights in biomarkers in allergic diseases and asthma

I Eguiluz‐Gracia, TR Tay, M Hew, MM Escribese… - Allergy, 2018 - Wiley Online Library
The potential of precision medicine in allergy and asthma has only started to be explored. A
significant clarification in the pathophysiology of rhinitis, chronic rhinosinusitis, asthma, food …

Budesonide irrigation with olfactory training improves outcomes compared with olfactory training alone in patients with olfactory loss

TP Nguyen, ZM Patel - International forum of allergy & rhinology, 2018 - Wiley Online Library
Background Olfactory training (OT) helps many patients with olfactory loss, but unfortunately
it is ineffective for a significant number of patients. Budesonide irrigations are widely used to …

Chronic interleukin‐13 expression in mouse olfactory mucosa results in regional aneuronal epithelium

A Saraswathula, MM Liu, H Kulaga… - International forum of …, 2023 - Wiley Online Library
Background Olfactory dysfunction is highly associated with chronic rhinosinusitis with nasal
polyps (CRSwNP), and the severity of loss has been linked with biomarkers of type 2 …

Correlation of mucus inflammatory proteins and olfaction in chronic rhinosinusitis

ZM Soler, F Yoo, RJ Schlosser… - International forum of …, 2020 - Wiley Online Library
Background Chronic rhinosinusitis (CRS) is one of the most common causes of olfactory
loss, but the pathophysiology underlying olfactory dysfunction in CRS has not been fully …

Olfactory and middle meatal cytokine levels correlate with olfactory function in chronic rhinosinusitis

J Wu, RK Chandra, P Li, BP Hull… - The Laryngoscope, 2018 - Wiley Online Library
Objectives/Hypothesis The etiology of chronic rhinosinusitis (CRS)‐associated olfactory loss
is unclear, but may result from inflammatory changes in the olfactory epithelium that result in …

Eosinophil extracellular trap formation is closely associated with disease severity in chronic rhinosinusitis regardless of nasal polyp status

CS Hwang, SC Park, HJ Cho, DJ Park, JH Yoon… - Scientific reports, 2019 - nature.com
Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory airway disease involving non-
eosinophilic and eosinophilic phenotypes, which translate to various endotypes. Activated …

Role of tissue eosinophils in chronic rhinosinusitis–associated olfactory loss

LJ Hauser, RK Chandra, P Li… - International forum of …, 2017 - Wiley Online Library
Background Olfactory dysfunction is 1 of the hallmark symptoms of chronic rhinosinusitis
(CRS). Eosinophilic inflammation has been implicated as a potential causative factor …