Riboswitches are structured noncoding RNA domains used by many bacteria to monitor the
concentrations of target ligands and regulate gene expression accordingly. In the past 20 …

With both catalytic and genetic functions, ribonucleic acid (RNA) is perhaps the most
pluripotent chemical species in molecular biology, and its functions are intimately linked to …

Fluoride is ubiquitously present throughout the world. It is released from minerals, magmatic
gas, and industrial processing, and travels in the atmosphere and water. Exposure to low …

Riboswitches are commonly used by bacteria to detect a variety of metabolites and ions to
regulate gene expression. To date, nearly 40 different classes of riboswitches have been …

Bacterial multidrug efflux pumps have come to prominence in human and veterinary
pathogenesis because they help bacteria protect themselves against the antimicrobials …

Riboswitches were discovered in 2002 in bacteria as RNA-based intracellular sensors of
vitamin derivatives. During the last decade, naturally occurring RNA sensor elements have …

Riboswitches are structured noncoding RNA domains that selectively bind metabolites and
control gene expression (;;). Nearly all examples of the known riboswitches reside in …

A growing collection of bacterial riboswitch classes is being discovered that sense central
metabolites, coenzymes, and signaling molecules. Included among the various mechanisms …

Most riboswitches are metabolite-binding RNA structures located in bacterial messenger
RNAs where they control gene expression. We have discovered a riboswitch class in many …

An expanding number of metabolite-binding riboswitch classes are being discovered in the
noncoding portions of bacterial genomes. Findings over the last decade indicate that …