Biosynthesis and biological functions of terpenoids in plants

D Tholl - Biotechnology of isoprenoids, 2015 - Springer
<? xm-replace_text {Heading}?> Abstract Terpenoids (isoprenoids) represent the largest
and most diverse class of chemicals among the myriad compounds produced by plants …

Base editing in crops: current advances, limitations and future implications

R Mishra, RK Joshi, K Zhao - Plant Biotechnology Journal, 2020 - Wiley Online Library
Targeted mutagenesis via genome‐editing technologies holds great promise in developing
improved crop varieties to meet future demands. Point mutations or single nucleotide …

Network analysis of the MVA and MEP pathways for isoprenoid synthesis

E Vranová, D Coman, W Gruissem - Annual review of plant …, 2013 - annualreviews.org
Isoprenoid biosynthesis is essential for all living organisms, and isoprenoids are also of
industrial and agricultural interest. All isoprenoids are derived from prenyl diphosphate …

High efficient multisites genome editing in allotetraploid cotton (Gossypium hirsutum) using CRISPR/Cas9 system

P Wang, J Zhang, L Sun, Y Ma, J Xu… - Plant biotechnology …, 2018 - Wiley Online Library
Gossypium hirsutum is an allotetraploid with a complex genome. Most genes have multiple
copies that belong to At and Dt subgenomes. Sequence similarity is also very high between …

Carotenoids and their cleavage products: biosynthesis and functions

MH Walter, D Strack - Natural product reports, 2011 - pubs.rsc.org
Covering: up to mid-2010 This review focuses on plant carotenoids, but it also includes
progress made on microbial and animal carotenoid metabolism to better understand the …

The 1-deoxy-D-xylulose-5-phosphate pathway of isoprenoid biosynthesis in plants

HK Lichtenthaler - Annual review of plant biology, 1999 - annualreviews.org
▪ Abstract In plants the biosynthesis of prenyllipids and isoprenoids proceeds via two
independent pathways:(a) the cytosolic classical acetate/mevalonate pathway for the …

Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics

M Rodrıguez-Concepción, A Boronat - Plant physiology, 2002 - academic.oup.com
Plants synthesize an enormous variety of metabolites that can be classified into two groups
based on their function: primary metabolites, which participate in nutrition and essential …

High‐efficient and precise base editing of C•G to T•A in the allotetraploid cotton (Gossypium hirsutum) genome using a modified CRISPR/Cas9 system

L Qin, J Li, Q Wang, Z Xu, L Sun… - Plant biotechnology …, 2020 - Wiley Online Library
The base‐editing technique using CRISPR/nC as9 (Cas9 nickase) or dC as9 (deactivated
Cas9) fused with cytidine deaminase is a powerful tool to create point mutations. In this …

Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs

H Jomaa, J Wiesner, S Sanderbrand, B Altincicek… - Science, 1999 - science.org
A mevalonate-independent pathway of isoprenoid biosynthesis present in Plasmodium
falciparum was shown to represent an effective target for chemotherapy of malaria. This …

A raison d'être for two distinct pathways in the early steps of plant isoprenoid biosynthesis?

A Hemmerlin, JL Harwood, TJ Bach - Progress in lipid research, 2012 - Elsevier
When compared to other organisms, plants are atypical with respect to isoprenoid
biosynthesis: they utilize two distinct and separately compartmentalized pathways to build …