Artificial intelligence-powered microfluidics for nanomedicine and materials synthesis
Artificial intelligence (AI) is an emerging technology with great potential, and its robust
calculation and analysis capabilities are unmatched by traditional calculation tools. With the …
calculation and analysis capabilities are unmatched by traditional calculation tools. With the …
AI-powered microfluidics: shaping the future of phenotypic drug discovery
J Liu, H Du, L Huang, W Xie, K Liu… - … Applied Materials & …, 2024 - ACS Publications
Phenotypic drug discovery (PDD), which involves harnessing biological systems directly to
uncover effective drugs, has undergone a resurgence in recent years. The rapid …
uncover effective drugs, has undergone a resurgence in recent years. The rapid …
A comparison of microfluidic methods for high-throughput cell deformability measurements
The mechanical phenotype of a cell is an inherent biophysical marker of its state and
function, with many applications in basic and applied biological research. Microfluidics …
function, with many applications in basic and applied biological research. Microfluidics …
[HTML][HTML] Cancer cells resist mechanical destruction in circulation via RhoA/actomyosin-dependent mechano-adaptation
During metastasis, cancer cells are exposed to potentially destructive hemodynamic forces
including fluid shear stress (FSS) while en route to distant sites. However, prior work …
including fluid shear stress (FSS) while en route to distant sites. However, prior work …
A review on recent advances of AI-integrated microfluidics for analytical and bioanalytical applications
In today's biomedical research, the pursuit of diagnostic tools boasting maximum precision
and accuracy while minimizing sample volume and pre-treatment requirements, has …
and accuracy while minimizing sample volume and pre-treatment requirements, has …
Cells nanomechanics by atomic force microscopy: focus on interactions at nanoscale
Nanomechanics of cytoskeleton is deeply involved in physiology and regulation of cell
behavior. Atomic Force Microscopy has been extensively used for quantitative …
behavior. Atomic Force Microscopy has been extensively used for quantitative …
A unified rheological model for cells and cellularised materials
A Bonfanti, J Fouchard… - Royal Society …, 2020 - royalsocietypublishing.org
The mechanical response of single cells and tissues exhibits a broad distribution of time-
scales that often gives rise to a distinctive power-law rheology. Such complex behaviour …
scales that often gives rise to a distinctive power-law rheology. Such complex behaviour …
[HTML][HTML] Cancer cell mechanobiology: a new frontier for cancer research
W Yu, S Sharma, E Rao, AC Rowat… - Journal of the National …, 2022 - Elsevier
The study of physical and mechanical features of cancer cells, or cancer cell
mechanobiology, is a new frontier in cancer research. Such studies may enhance our …
mechanobiology, is a new frontier in cancer research. Such studies may enhance our …
Fluid shear stress coupled with narrow constrictions induce cell type-dependent morphological and molecular changes in SK-BR-3 and MDA-MB-231 cells
HA Cognart, JL Viovy, C Villard - Scientific reports, 2020 - nature.com
Cancer mortality mainly arises from metastases, due to cells that escape from a primary
tumor, circulate in the blood as circulating tumor cells (CTCs), permeate across blood …
tumor, circulate in the blood as circulating tumor cells (CTCs), permeate across blood …
Glioma Single-Cell Biomechanical Analysis by Cyclic Conical Constricted Microfluidics
X Geng, ZA Zhou, Y Mi, C Wang, M Wang… - Analytical …, 2023 - ACS Publications
Determining the grade of glioma is a critical step in choosing patients' treatment plans in
clinical practices. The pathological diagnosis of patient's glioma samples requires extensive …
clinical practices. The pathological diagnosis of patient's glioma samples requires extensive …