Antifungal effects of statins

A Tavakkoli, TP Johnston, A Sahebkar - Pharmacology & therapeutics, 2020 - Elsevier
Fungal infections are estimated to be responsible for 1.5 million deaths annually. Global anti-
microbial resistance is also observed for fungal pathogens, and scientists are looking for …

Can nonsteroidal anti-inflammatory drugs (NSAIDs) be repurposed for fungal infection?

F Babaei, M Mirzababaei, A Tavakkoli… - Naunyn-Schmiedeberg's …, 2024 - Springer
Nonsteroidal anti-inflammatory drugs (NSAIDs) are an important class of anti-inflammatory
drugs widely used for the treatment of musculoskeletal disorders, mild-to-moderate pain …

Treatment outcomes of surgery, antifungal therapy and immunotherapy in ocular and vascular human pythiosis: a retrospective study of 18 patients

N Permpalung, N Worasilchai, R Plongla… - Journal of …, 2015 - academic.oup.com
Objectives Human pythiosis is a life-threatening disease for which no standard treatment
protocols with proven efficacy exist. We present the results of our institutional pythiosis …

Review of methods and antimicrobial agents for susceptibility testing against Pythium insidiosum

H Yolanda, T Krajaejun - Heliyon, 2020 - cell.com
Pythiosis is a life-threatening infectious disease of humans and animals caused by the
oomycete microorganism Pythium insidiosum. The disease has been increasingly …

New Insights into the In Vitro Susceptibility of Pythium insidiosum

ÉS Loreto, JSM Tondolo, MB Pilotto… - Antimicrobial Agents …, 2014 - Am Soc Microbiol
We have determined the in vitro activity of several antibacterial and antifungal drugs against
Pythium insidiosum using broth microdilution (BMD), disk diffusion, and Etest methods. The …

Invasive fungal infections and oomycoses in cats 2. Antifungal therapy

VR Barrs, S Hobi, A Wong, J Sandy… - Journal of Feline …, 2024 - journals.sagepub.com
Clinical relevance: Invasive fungal infections (IFIs) and oomycoses (hereafter termed
invasive fungal-like infections [IFLIs]) are characterised by penetration of tissues by fungal …

In Vitro and In Vivo Antimicrobial Activities of Minocycline in Combination with Azithromycin, Clarithromycin, or Tigecycline against Pythium insidiosum

FPK Jesus, ÉS Loreto, L Ferreiro… - Antimicrobial Agents …, 2016 - Am Soc Microbiol
The present study investigated the in vitro and the in vivo interactions among azithromycin,
clarithromycin, minocycline, and tigecycline against Pythium insidiosum. In vitro …

In vitro activity of carvacrol and thymol combined with antifungals or antibacterials against Pythium insidiosum

FPK Jesus, L Ferreiro, KS Bizzi, ÉS Loreto… - Journal de Mycologie …, 2015 - Elsevier
We describe the in vitro activities of the combinations of carvacrol and thymol with antibiotics
(azithromycin, clarithromycin, minocycline and tigecycline) and antifungal agents …

Fluconazole-Loaded Ibuprofen In Situ Gel-Based Oral Spray for Oropharyngeal Candidiasis Treatment

EM Khaing, S Senarat, K Jitrangsri, T Phaechamud - AAPS PharmSciTech, 2024 - Springer
Oral candidiasis is a fungal infection affecting the oral mucous membrane, and this research
specifically addresses on a localized treatment through fluconazole-loaded ibuprofen in situ …

Clinical outcomes in ocular pythiosis patients treated with a combination therapy protocol in Thailand: a prospective study

N Permpalung, N Worasilchai… - Medical …, 2019 - academic.oup.com
Ocular pythiosis is the second most common form of human pythiosis, and the rates of
evisceration/enucleation in Thailand are 55–79%. This prospective study was conducted to …