Regulatory mechanisms of exopolysaccharide synthesis and biofilm formation in Streptococcus mutans

T Zheng, M Jing, T Gong, J Yan, X Wang… - Journal of Oral …, 2023 - Taylor & Francis
Background Dental caries is a chronic, multifactorial and biofilm-mediated oral bacterial
infection affecting almost every age group and every geographical region. Streptococcus …

Dual role of humic substances as electron donor and shuttle for dissimilatory iron reduction

N Stern, J Mejia, S He, Y Yang… - … science & technology, 2018 - ACS Publications
Dissimilatory iron-reducing bacteria (DIRB) are known to use humic substances (HS) as
electron shuttles for dissimilatory iron reduction (DIR) by transferring electrons to HS …

Microbial dextran-hydrolyzing enzyme: Properties, structural features, and versatile applications

Z Chen, J Chen, D Ni, W Xu, W Zhang, W Mu - Food Chemistry, 2023 - Elsevier
Dextran, an α-glucan mainly composed of (α1→ 6) linkages, has been widely applied in the
food, cosmetic, and medicine industries. Dextranase can hydrolyze dextran to synthesize …

Bacteroidota polysaccharide utilization system for branched dextran exopolysaccharides from lactic acid bacteria

S Nakamura, R Kurata, T Tonozuka, K Funane… - Journal of Biological …, 2023 - ASBMB
Dextran is an α-(1→ 6)-glucan that is synthesized by some lactic acid bacteria, and
branched dextran with α-(1→ 2)-, α-(1→ 3)-, and α-(1→ 4)-linkages are often produced …

Heterologous overproduction of a dextranase in Bacillus subtilis WB600 and its application in preparation of porous buckwheat starch

M Liu, Y Hao, S Wang, S Li, J Zhou, L Zhang, X Kang… - Food Bioscience, 2024 - Elsevier
The hydrolysis product of dextranase contains highly polymerized oligomeric isomaltose,
which can be used as prebiotics to promote the colonization of probiotics, thus adjusting the …

Structural basis for biofilm formation via the Vibrio cholerae matrix protein RbmA

KM Giglio, JC Fong, FH Yildiz… - Journal of …, 2013 - Am Soc Microbiol
During the transition from a free-swimming, single-cell lifestyle to a sessile, multicellular
state called a biofilm, bacteria produce and secrete an extracellular matrix comprised of …

Development of thermostable dextranase from Streptococcus mutans (SmdexTM) through in silico design employing B-factor and Cartesian-ΔΔG

WJ Ru, BB Xia, YX Zhang, JW Yang, HB Zhang… - Journal of …, 2022 - Elsevier
The thermal stability of enzymes dramatically limits their application in the industrial field.
Based on the crystal structure, we conducted a semi-rational design according to the B …

Crystal Structure of GH49 Dextranase from Arthrobacter oxidans KQ11: Identification of Catalytic Base and Improvement of Thermostability Using Semirational Design Based on …

W Ren, L Liu, L Gu, W Yan, Y Feng… - Journal of agricultural …, 2019 - ACS Publications
The crystal structure of Dextranase from the marine bacterium Arthrobacter oxidans KQ11
(Aodex) was determined at a resolution of 1.4 Å. The crystal structure of the conserved …

Dental caries

RJ Lamont, PG Egland - Molecular medical microbiology, 2015 - Elsevier
Dental caries is an infectious disease that results in demineralization of the tooth and the
formation of cavities. The aetiology of caries is multifactorial and involves host factors such …

Sucrose selectively regulates Streptococcus mutans polysaccharide by GcrR

H Zhang, M Xia, B Zhang, Y Zhang… - Environmental …, 2022 - Wiley Online Library
Streptococcus mutans (S. mutans) is the principal etiological agent in cariogenesis because
of its ability to metabolize sucrose into extracellular polysaccharides (EPS). The response …