[HTML][HTML] Pathophysiology of obesity and its associated diseases
The occurrence of obesity has increased across the whole world. Many epidemiological
studies have indicated that obesity strongly contributes to the development of cancer …
studies have indicated that obesity strongly contributes to the development of cancer …
The diversity and breadth of cancer cell fatty acid metabolism
Tumor cellular metabolism exhibits distinguishing features that collectively enhance
biomass synthesis while maintaining redox balance and cellular homeostasis. These …
biomass synthesis while maintaining redox balance and cellular homeostasis. These …
Phosphatidylcholine-derived lipid mediators: The crosstalk between cancer cells and immune cells
RF Saito, LNS Andrade, SO Bustos… - Frontiers in …, 2022 - frontiersin.org
To become resistant, cancer cells need to activate and maintain molecular defense
mechanisms that depend on an energy trade-off between resistance and essential functions …
mechanisms that depend on an energy trade-off between resistance and essential functions …
Why make it if you can take it: review on extracellular cholesterol uptake and its importance in breast and ovarian cancers
AR Lauridsen, A Skorda, NI Winther, ML Bay… - Journal of Experimental …, 2024 - Springer
Cholesterol homeostasis is essential for healthy mammalian cells and dysregulation of
cholesterol metabolism contributes to the pathogenesis of various diseases including …
cholesterol metabolism contributes to the pathogenesis of various diseases including …
Lipid metabolism and cancer
H Cheng, M Wang, J Su, Y Li, J Long, J Chu, X Wan… - Life, 2022 - mdpi.com
Lipid metabolism is involved in the regulation of numerous cellular processes, such as cell
growth, proliferation, differentiation, survival, apoptosis, inflammation, movement, membrane …
growth, proliferation, differentiation, survival, apoptosis, inflammation, movement, membrane …
Reprogrammed lipid metabolism and the lipid-associated hallmarks of colorectal cancer
Simple Summary Colorectal cancer (CRC) is the third-most diagnosed cancer and the
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …
second-leading cause of cancer-related deaths worldwide. Limitations in early and accurate …
Targeting lipid metabolism in metastatic prostate cancer
T Scheinberg, B Mak, L Butler… - … Advances in Medical …, 2023 - journals.sagepub.com
Despite key advances in the treatment of prostate cancer (PCa), a proportion of men have
de novo resistance, and all will develop resistance to current therapeutics over time …
de novo resistance, and all will develop resistance to current therapeutics over time …
[HTML][HTML] Plasma lipids signify the progression of precancerous gastric lesions to gastric cancer: a prospective targeted lipidomics study
Rationale: Gastric cancer (GC) is preceded by a stepwise progression of precancerous
gastric lesions. Distinguishing individuals with precancerous gastric lesions that have …
gastric lesions. Distinguishing individuals with precancerous gastric lesions that have …
Therapeutic potential of NR4A1 in cancer: Focus on metabolism
S Deng, B Chen, J Huo, X Liu - Frontiers in oncology, 2022 - frontiersin.org
Metabolic reprogramming is a vital hallmark of cancer, and it provides the necessary energy
and biological materials to support the continuous proliferation and survival of tumor cells …
and biological materials to support the continuous proliferation and survival of tumor cells …
Diet modulates the gut microbiome, metabolism, and mammary gland inflammation to influence breast cancer risk
AA Arnone, AS Wilson, DR Soto-Pantoja… - Cancer Prevention …, 2024 - aacrjournals.org
Several studies indicate a strong link between obesity and the risk of breast cancer. Obesity
decreases gut microbial biodiversity and modulates Bacteroidetes-to-Firmicutes phyla …
decreases gut microbial biodiversity and modulates Bacteroidetes-to-Firmicutes phyla …