Microbiota-brain-gut axis and neurodegenerative diseases

EMM Quigley - Current neurology and neuroscience reports, 2017 - Springer
Abstract Purpose of Review The purposes of this review were as follows: first, to provide an
overview of the gut microbiota and its interactions with the gut and the central nervous …

[HTML][HTML] Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review

C Stillhart, K Vučićević, P Augustijns, AW Basit… - European Journal of …, 2020 - Elsevier
The release and absorption profile of an oral medication is influenced by the
physicochemical properties of the drug and its formulation, as well as by the anatomy and …

[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs

X Zhang, Y Han, W Huang, M Jin, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …

[HTML][HTML] The gut microbiome: an orchestrator of xenobiotic metabolism

SL Collins, AD Patterson - Acta Pharmaceutica Sinica B, 2020 - Elsevier
Microbes inhabiting the intestinal tract of humans represent a site for xenobiotic metabolism.
The gut microbiome, the collection of microorganisms in the gastrointestinal tract, can alter …

Gut microbiota: Implications in Parkinson's disease

A Parashar, M Udayabanu - Parkinsonism & related disorders, 2017 - Elsevier
Gut microbiota (GM) can influence various neurological outcomes, like cognition, learning,
and memory. Commensal GM modulates brain development and behavior and has been …

Parkinson's disease and the gastrointestinal microbiome

M Lubomski, AH Tan, SY Lim, AJ Holmes, RL Davis… - Journal of …, 2020 - Springer
Recently, there has been a surge in awareness of the gastrointestinal microbiome (GM) and
its role in health and disease. Of particular note is an association between the GM and …

[HTML][HTML] Probiotics for Parkinson's disease

P Gazerani - International journal of molecular sciences, 2019 - mdpi.com
Parkinson's disease (PD) is a complex neurological disorder classically characterized by
impairments in motor system function associated with loss of dopaminergic neurons in the …

Gastrointestinal barriers to levodopa transport and absorption in Parkinson's disease

V Leta, L Klingelhoefer, K Longardner… - European Journal of …, 2023 - Wiley Online Library
Levodopa is the gold standard for the symptomatic treatment of Parkinson's disease (PD).
There are well documented motor and non‐motor fluctuations, however, that occur almost …

Microbiota-gut-brain signalling in Parkinson's disease: Implications for non-motor symptoms

VD Felice, EM Quigley, AM Sullivan… - Parkinsonism & related …, 2016 - Elsevier
Parkinson's disease is the second most common neurodegenerative disorder, affecting 1–
2% of the population over 65 years of age. The primary neuropathology is the loss of …

Interactions between the microbiota and enteric nervous system during gut-brain disorders

S Fried, E Wemelle, PD Cani, C Knauf - Neuropharmacology, 2021 - Elsevier
For the last 20 years, researchers have focused their intention on the impact of gut
microbiota in healthy and pathological conditions. This year (2021), more than 25,000 …