Liposomes and polymersomes: a comparative review towards cell mimicking

E Rideau, R Dimova, P Schwille, FR Wurm… - Chemical society …, 2018 - pubs.rsc.org
Cells are integral to all forms of life due to their compartmentalization by the plasma
membrane. However, living organisms are immensely complex. Thus there is a need for …

Neuronal lipid metabolism: multiple pathways driving functional outcomes in health and disease

TJ Tracey, FJ Steyn, EJ Wolvetang… - Frontiers in molecular …, 2018 - frontiersin.org
Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …

How can we use the endocytosis pathways to design nanoparticle drug-delivery vehicles to target cancer cells over healthy cells?

VT Cong, JL Houng, M Kavallaris, X Chen… - Chemical Society …, 2022 - pubs.rsc.org
Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …

Phagocytic microglia and macrophages in brain injury and repair

F Yu, Y Wang, AR Stetler, RK Leak… - CNS neuroscience & …, 2022 - Wiley Online Library
Aims Phagocytosis is the cellular digestion of extracellular particles, such as pathogens and
dying cells, and is a key element in the evolution of central nervous system (CNS) disorders …

[HTML][HTML] How particular is the physics of the free energy principle?

M Aguilera, B Millidge, A Tschantz, CL Buckley - Physics of Life Reviews, 2022 - Elsevier
The free energy principle (FEP) states that any dynamical system can be interpreted as
performing Bayesian inference upon its surrounding environment. Although, in theory, the …

Mechanistic landscape of membrane-permeabilizing peptides

S Guha, J Ghimire, E Wu, WC Wimley - Chemical reviews, 2019 - ACS Publications
Membrane permeabilizing peptides (MPPs) are as ubiquitous as the lipid bilayer
membranes they act upon. Produced by all forms of life, most membrane permeabilizing …

The dynamics of apoptotic cell clearance

MR Elliott, KS Ravichandran - Developmental cell, 2016 - cell.com
The phagocytic clearance of dying cells in a tissue is a highly orchestrated series of
intercellular events coordinated by a complex signaling network. Recent data from genetic …

Platelets and their role in hemostasis and thrombosis—From physiology to pathophysiology and therapeutic implications

A Scridon - International Journal of Molecular Sciences, 2022 - mdpi.com
Hemostasis is a physiological process critical for survival. Meanwhile, thrombosis is
amongst the leading causes of death worldwide, making antithrombotic therapy one of the …

The 2018 biomembrane curvature and remodeling roadmap

P Bassereau, R Jin, T Baumgart… - Journal of physics D …, 2018 - iopscience.iop.org
The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …

Phosphatidylserine: A cancer cell targeting biomarker

B Sharma, SS Kanwar - Seminars in cancer biology, 2018 - Elsevier
Cancer is a leading cause of mortality and morbidity globally. Many prominent cancer-
associated molecules have been identified over the recent years which include EGFR …