Differentiation of human mesenchymal stem cells towards neuronal lineage: clinical trials in nervous system disorders

R Hernández, C Jiménez-Luna… - Biomolecules & …, 2019 - pmc.ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) have been proposed as an alternative therapy to be
applied into several pathologies of the nervous system. These cells can be obtained from …

Fibrin as a delivery system for therapeutic drugs and biomolecules

A Breen, T O'Brien, A Pandit - Tissue Engineering Part B: Reviews, 2009 - liebertpub.com
Fibrin is a natural biopolymer involved in the coagulation cascade. It acts as a reservoir for
growth factors, cells, and enzymes during wound healing and provides a scaffold for the …

Mesenchymal stem cell-derived magnetic extracellular nanovesicles for targeting and treatment of ischemic stroke

HY Kim, TJ Kim, L Kang, YJ Kim, MK Kang, J Kim… - Biomaterials, 2020 - Elsevier
Exosomes and extracellular nanovesicles (NV) derived from mesenchymal stem cells (MSC)
may be used for the treatment of ischemic stroke owing to their multifaceted therapeutic …

Targeted delivery of mesenchymal stem cell-derived nanovesicles for spinal cord injury treatment

JR Lee, JW Kyung, H Kumar, SP Kwon… - International Journal of …, 2020 - mdpi.com
Due to the safety issues and poor engraftment of mesenchymal stem cell (MSC)
implantation, MSC-derived exosomes have been spotlighted as an alternative therapy for …

Advances in natural biomaterials for nerve tissue repair

ZZ Khaing, CE Schmidt - Neuroscience letters, 2012 - Elsevier
Natural biomaterials are well positioned to play a significant role in the development of the
next generation of biomaterials for nervous system repair. These materials are derived from …

Cell-based therapy for traumatic brain injury

S Gennai, A Monsel, Q Hao, J Liu… - British journal of …, 2015 - academic.oup.com
Traumatic brain injury is a major economic burden to hospitals in terms of emergency
department visits, hospitalizations, and utilization of intensive care units. Current guidelines …

Creating permissive microenvironments for stem cell transplantation into the central nervous system

H Kim, MJ Cooke, MS Shoichet - Trends in biotechnology, 2012 - cell.com
Traumatic injury to the central nervous system (CNS) is highly debilitating, with the clinical
need for regenerative therapies apparent. Neural stem/progenitor cells (NSPCs) are …

Traumatic brain injury in the elderly: is it as bad as we think?

CHK Mak, SKH Wong, GK Wong, S Ng… - Current translational …, 2012 - Springer
Traumatic brain injury in elderly patients is a neglected global disease burden. The main
cause is fall, followed by motor vehicle accidents. This review article summarizes different …

Synergistic coating strategy combining photodynamic therapy and fluoride-free superhydrophobicity for eradicating bacterial adhesion and reinforcing corrosion …

W Wang, MS Song, XN Yang, J Zhao… - … applied materials & …, 2020 - ACS Publications
Device-associated infection is one of the significant challenges in the biomedical industry
and clinical management. Controlling the initial attachment of microbes upon the solid …

EGF/bFGF promotes survival, migration and differentiation into neurons of GFP-labeled rhesus monkey neural stem cells xenografted into the rat brain

H Li, X Gan, L Pan, Y Zhang, X Hu, Z Wang - Biochemical and biophysical …, 2022 - Elsevier
Stem cell replacement therapy is considered a promising treatment for diseases of the
central nervous system. Improving the ratio of surviving transplanted cells and the efficiency …