Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …

Colorectal cancer (CRC) is the third most common cancer and the fourth most common
cause of cancer-related death. Most cases of CRC are detected in Western countries, with its …

A new era of metal-based drugs started in the 1960s, heralded by the discovery of potent
platinum-based complexes, commencing with cisplatin [(H3N) 2PtCl2], which are effective …

Gold-based anticancer agents have gained the widespread attention of medicinal inorganic
chemists due to their unique chemical properties and strong antiproliferative potency …

Auranofin (AF), a gold compound, has been used to treat rheumatoid arthritis (RA) for more
than 40 years; however, its mechanism of action remains unknown. We revealed that AF …

The advent of the clinically approved drug cisplatin started a new era in the design of
metallodrugs for cancer chemotherapy. However, to date, there has not been much success …

New weapons are constantly needed in the fight against cancer. The discovery of cisplatin
as an anticancer drug prompted the search for new metal complexes. The successful history …

Since ancient times gold and its complexes have been used as therapeutics against
different diseases. In modern medicine gold drugs have been applied for the treatment of …

Organometallic complexes have widely been used for the treatment of various diseases viz.,
malaria, arthritis, syphilis, pernicious anemia, tuberculosis and particular in cancers. Recent …

Background: Since the serendipitous discovery of the antitumor activity of cisplatin there has
been a continuous surge in studies aimed at the development of new cytotoxic metal …