ETS-related gene (ERG) is a member of the E-26 transformation-specific (ETS) family of
transcription factors with roles in development that include vasculogenesis, angiogenesis …

The helix-turn-helix (HTH) domain is a common denominator in basal and specific
transcription factors from the three super-kingdoms of life. At its core, the domain comprises …

Widespread adoption of mirror-image biological systems presents difficulties in accessing
the requisite D-protein substrates. In particular, mirror-image phage display has the potential …

ETS proteins are a group of evolutionarily related, DNA-binding transcriptional factors.
These proteins direct gene expression in diverse normal and disease states by binding to …

Ets1 belongs to the large family of the ETS domain family of transcription factors and is
involved in cancer progression. In most carcinomas, Ets1 expression is linked to poor …

The Ets1 transcription factor is a member of the Ets gene family and is highly conserved
throughout evolution. Ets1 is known to regulate a number of important biological processes …

The androgen receptor (AR) is a nuclear receptor that governs gene expression programs
required for prostate development and male phenotype maintenance. Advanced prostate …

Transcription factors provide nodes of information integration by serving as nuclear effectors
of multiple signaling cascades, and thus elaborate layers of regulation, often involving post …

There is growing evidence supporting an inherited basis for susceptibility to acute
lymphoblastic leukemia (ALL) in children. In particular, we and others reported recurrent …

Cell signaling affects gene expression by regulating the activity of transcription factors. Here,
we report that mitogen-activated protein kinase (MAPK) phosphorylation of Ets-1 and Ets-2 …