The problem of exclusion or underrepresentation of women in clinical trials has remained an
open question over time. In his special report published in the New England Journal of …

Materials and methods: The chronomodulated system comprised of dual approach;
immediate release granules (IRG) and pulsatile release mini-tablets (PRM) filled in the hard …

We investigated the influence of early awakening and related factors on onset of
cerebrovascular disease (CVD). Totally 1199 stroke patients, in whom the onset time was …

Oral pulsatile drug delivery systems (PDDS) offer a promising approach to
chronotherapeutic goals, particularly for managing chronic diseases with nocturnal …

Background: Rapid urbanization of rural areas is predicted to increase the incidence of risk
factors for vascular events such as stroke among the ruralites. A different culture, beliefs …

Stroke is the culmination of a heterogene cerebrovascular diseases that is manifested a
hemorrhage of one or more blood vessels The incidence of stroke exhibits the circadia and …

Sleep disruption has been implicated in morbidity after major surgery since 1974. Sleep-
related upper airway obstruction has been associated with death after upper airway surgery …