Autophagy refers to the formation of autophagosomes by membrane wrapping part of the
cytoplasm and the organelles and proteins that need to be degraded in the cells …

Autophagy is central to the maintenance of organismal homeostasis in both physiological
and pathological situations. Accordingly, alterations in autophagy have been linked to …

The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

Autophagy and inflammation are 2 fundamental biological processes involved in both
physiological and pathological conditions. Through its crucial role in maintaining cellular …

Respiratory fungal infection is a severe clinical problem, especially in patients with
compromised immune functions. Aspergillus, Cryptococcus, Pneumocystis, and endemic …

Concealing pathogen-associated molecular patterns (PAMPs) is a principal strategy used by
fungi to avoid immune recognition. Surface exposure of PAMPs during germination can …

C ryptococcus is a potentially fatal fungal pathogen and a leading cause of death in
immunocompromised patients. As an opportunistic and facultative intracellular pathogen of …

Autophagy is a highly conserved lysosomal degradation system that involves the creation of
autophagosomes, which eventually fuse with lysosomes and breakdown misfolded proteins …

Phagocytes ingest, kill and degrade invading microbes in a process called phagocytosis.
LC3-associated phagocytosis (LAP) combines the molecular machinery of phagocytosis …

Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …