Emerging adjuvants for intradermal vaccination

X Chen - International Journal of Pharmaceutics, 2023 - Elsevier
The majority of vaccines have been delivered into the muscular tissue. Skin contains large
amounts of antigen-presenting cells and has been recognized as a more immunogenic site …

Selenium and zinc alleviate hepatotoxicity induced by heavy metal mixture (cadmium, mercury, lead and arsenic) via attenuation of inflammo‐oxidant pathways

H Ozoani, AN Ezejiofor, KO Okolo… - Environmental …, 2024 - Wiley Online Library
Heavy metals (HM) are believed to be injurious to humans. Man is exposed to them on daily
basis unknowingly, with no acceptable protocol to manage its deleterious effects. These …

CpG 1018 Is an Effective Adjuvant for Influenza Nucleoprotein

Y Li, X Chen - Vaccines, 2023 - mdpi.com
Current influenza vaccines mainly induce neutralizing antibodies against the highly variable
surface antigen hemagglutinin and require annual manufacturing and immunization …

Differential Regulation of DC Function, Adaptive Immunity, and MyD88 Dependence by MF59 and AS03-like Adjuvants

JR Nakkala, Y Li, L Akter, X Kang, X Chen - Vaccines, 2024 - mdpi.com
MF59 and AS03 are squalene emulsion-based vaccine adjuvants with similar compositions
and droplet sizes. Despite their broad use in licensed influenza vaccines, few studies …

[PDF][PDF] CpG 1018 Is an Effective Adjuvant for Influenza Nucleoprotein. Vaccines 2023, 11, 649

Y Li, X Chen - 2023 - pdfs.semanticscholar.org
Current influenza vaccines mainly induce neutralizing antibodies against the highly variable
surface antigen hemagglutinin and require annual manufacturing and immunization …

[HTML][HTML] Protocol for preparing murine tissue for comparative proteomics study of vaccine adjuvant mechanisms

Y Li, X Chen - STAR protocols, 2023 - Elsevier
Understanding the mechanisms of action of adjuvants at the tissue level is crucial to the
development of more potent and safer versions for human use. Comparative tissue …