Traffic control: regulation of kinesin motors

KJ Verhey, JW Hammond - Nature reviews Molecular cell biology, 2009 - nature.com
Kinesins are a family of molecular motors that use the energy of ATP hydrolysis to move
along the surface of, or destabilize, microtubule filaments. Much progress has been made in …

Mechanism and regulation of kinesin motors

A Yildiz - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Kinesins are a diverse superfamily of microtubule-based motors that perform fundamental
roles in intracellular transport, cytoskeletal dynamics and cell division. These motors share a …

Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease

K Shahpasand, I Uemura, T Saito, T Asano… - Journal of …, 2012 - Soc Neuroscience
The microtubule-associated protein Tau is a major component of the neurofibrillary tangles
that serve as a neuropathological hallmark of Alzheimer's disease. Tau is a substrate for …

Tau protein diffuses along the microtubule lattice

MH Hinrichs, A Jalal, B Brenner, E Mandelkow… - Journal of Biological …, 2012 - ASBMB
Current models for the intracellular transport of Tau protein suggest motor protein-
dependent co-transport with microtubule fragments and diffusion of Tau in the cytoplasm …

Microtubule organization by the antagonistic mitotic motors kinesin-5 and kinesin-14

C Hentrich, T Surrey - Journal of Cell Biology, 2010 - rupress.org
During cell division, different molecular motors act synergistically to rearrange microtubules.
Minus end–directed motors are thought to have a dual role: focusing microtubule ends to …

Molecular mechanisms of kinesin-14 motors in spindle assembly and chromosome segregation

ZY She, WX Yang - Journal of cell science, 2017 - journals.biologists.com
During eukaryote cell division, molecular motors are crucial regulators of microtubule
organization, spindle assembly, chromosome segregation and intracellular transport. The …

Regulation of ciliary homeostasis by intraflagellar transport-independent kinesins

L Li, J Ran - Cell Death & Disease, 2024 - nature.com
Cilia are highly conserved eukaryotic organelles that protrude from the cell surface and are
involved in sensory perception, motility, and signaling. Their proper assembly and function …

Clustering of centralspindlin is essential for its accumulation to the central spindle and the midbody

A Hutterer, M Glotzer, M Mishima - Current biology, 2009 - cell.com
Cytokinesis in animal cells requires the central spindle and midbody, which contain
prominent microtubule bundles [1]. Centralspindlin, a heterotetrameric complex consisting of …

Mitotic microtubule crosslinkers: insights from mechanistic studies

EJG Peterman, JM Scholey - Current Biology, 2009 - cell.com
Mitosis depends on the mitotic spindle, a subcellular protein machine that uses dynamic
microtubules and mitotic motors to assemble itself and to coordinate chromosome …

Biomolecular-motor-based autonomous delivery of lipid vesicles as nano-or microscale reactors on a chip

S Hiyama, Y Moritani, R Gojo, S Takeuchi, K Sutoh - Lab on a Chip, 2010 - pubs.rsc.org
We aimed to create an autonomous on-chip system that performs targeted delivery of lipid
vesicles (liposomes) as nano-or microscale reactors using machinery from biological …