Lipid droplets (LDs) are cellular organelles that are essential for maintaining lipid and
energy homeostasis. Once regarded as merely inert fat particles, they are now recognized …

BACKGROUND Biomolecules can serve as natural labels for microscopy by measuring their
molecular vibration spectra in living cells and tissues. However, the transition from …

Altered lipid metabolism is increasingly recognized as a signature of cancer cells. Enabled
by label-free Raman spectromicroscopy, we performed quantitative analysis of lipogenesis …

Lipid droplets (LDs) are organelles that have evolved to store intracellular neutral lipids and
maintain cellular energy homeostasis. Once considered as inert fat particles, they have …

In his 1665 treatise, Micrographia, Robert Hooke described the many observations he had
made using a microscope, including compartment-like structures in cork samples that he …

Visualizing and dynamic tracking lipid droplets (LDs) are of great importance to biological
research. Herein, two-photon absorption fluorescent small bioprobes based on lipophilic …

Cellular biomolecules contain unique molecular vibrations that can be visualized by
coherent anti-Stokes Raman scattering (CARS) microscopy without the need for labels. Here …

Lipid droplets (LDs) as dynamic organelles are associated with many metabolic processes.
Ideal fluorescent probes for LD-specific imaging require excellent specificity, superior …

Background Excess storage of lipids in ectopic tissues, such as skeletal muscle, liver, and
heart, seems to associate closely with metabolic abnormalities and cardiac disease …

Recently, tetraphenylethene, triphenylamine and other man-made core AIE luminescent
materials (AIEgens) have attracted significant scientific interest. However, the design and …