Use of AgomiR and AntagomiR technologies to alter satellite cell proliferation in vitro, miRNA expression, and muscle fiber hypertrophy in intrauterine growth …

MA Greene, GA Worley, ANS Udoka… - Frontiers in Molecular …, 2023 - frontiersin.org
Introduction: microRNAs (miRNAs) are small non-coding RNAs that work at the
posttranscriptional level to repress gene expression. Several miRNAs are preferentially …

Genetic manipulation of CB1 cannabinoid receptors reveals a role in maintaining proper skeletal muscle morphology and function in mice

Z Singlár, N Ganbat, P Szentesi… - International Journal of …, 2022 - mdpi.com
The endocannabinoid system (ECS) refers to a widespread signaling system and its
alteration is implicated in a growing number of human diseases. Cannabinoid receptors …

Reduced Expression of Septin7 Hinders Skeletal Muscle Regeneration

L Szabó, A Telek, J Fodor, N Dobrosi, K Dócs… - International Journal of …, 2023 - mdpi.com
Septins are considered the fourth component of the cytoskeleton with the septin7 isoform
playing a critical role in the formation of diffusion barriers in phospholipid bilayers and intra …

Implication of microRNAs as messengers of exercise adaptation in junior female triathlonists

Z Gaál, J Fodor, T Oláh, IG Szabó, I Balatoni… - Scientific Reports, 2024 - nature.com
While expression profile of muscle-specific miRNAs following endurance training is well-
characterized, information about exercise-induced changes of metabolism-regulating …

Migration of Myogenic Cells Is Highly Influenced by Cytoskeletal Septin7

Z Ráduly, L Szabó, B Dienes, P Szentesi, ÁV Bana… - Cells, 2023 - mdpi.com
Septin7 as a unique member of the GTP binding protein family, is widely expressed in the
eukaryotic cells and considered to be essential in the formation of hetero-oligomeric septin …

[HTML][HTML] Dynamic remodeling of septin structures fine-tunes myogenic differentiation

V Ugorets, PL Mendez, D Zagrebin, G Russo… - Iscience, 2024 - cell.com
Controlled myogenic differentiation is integral to the development, maintenance and repair
of skeletal muscle, necessitating precise regulation of myogenic progenitors and resident …

LncRNA microarray profiling identifies novel circulating lncRNAs in hidradenitis suppurativa

B De Felice, P De Luca… - Molecular …, 2024 - spandidos-publications.com
Long noncoding RNAs (lncRNAs) have been demonstrated to be involved in biological
processes, both physiological and pathological, including cancer, cardiovascular diseases …

Septin 7 interacts with Numb to preserve sarcomere structural organization and muscle contractile function

R De Gasperi, L Csernoch, B Dienes, M Gonczi… - Elife, 2024 - elifesciences.org
Here, we investigated the mechanisms by which aging-related reductions of the levels of
Numb in skeletal muscle fibers contribute to loss of muscle strength and power, two critical …

Reorganization of Septin structures regulates early myogenesis

V Ugorets, PL Mendez, D Zagrebin, G Russo… - bioRxiv, 2023 - biorxiv.org
Controlled myogenic differentiation is crucial for developmental formation, homeostatic
maintenance and adult repair of skeletal muscle and relies on cell fate determinants in …

Septins regulate heart contractility through modulation of cardiomyocyte store-operated calcium entry

BA Tripoli, JT Smyth - bioRxiv, 2024 - biorxiv.org
Highly regulated cardiomyocyte Ca2+ fluxes drive heart contractions. Recent findings from
multiple organisms demonstrate that the specific Ca2+ transport mechanism known as store …