Data mining in healthcare: Applying strategic intelligence techniques to depict 25 years of research development

ML Kolling, LB Furstenau, MK Sott, B Rabaioli… - International journal of …, 2021 - mdpi.com
In order to identify the strategic topics and the thematic evolution structure of data mining
applied to healthcare, in this paper, a bibliometric performance and network analysis …

Application of artificial intelligence techniques to predict risk of recurrence of breast cancer: a systematic review

C Mazo, C Aura, A Rahman, WM Gallagher… - Journal of Personalized …, 2022 - mdpi.com
Breast cancer is the most common disease among women, with over 2.1 million new
diagnoses each year worldwide. About 30% of patients initially presenting with early stage …

[HTML][HTML] BAG3 overexpression and cytoprotective autophagy mediate apoptosis resistance in chemoresistant breast cancer cells

CK Das, B Linder, F Bonn, F Rothweiler, I Dikic… - Neoplasia, 2018 - Elsevier
Target-specific treatment modalities are currently not available for triple-negative breast
cancer (TNBC), and acquired chemotherapy resistance is a primary obstacle for the …

Six novel immunoglobulin genes as biomarkers for better prognosis in triple-negative breast cancer by gene co-expression network analysis

HM Hsu, CM Chu, YJ Chang, JC Yu, CT Chen… - Scientific reports, 2019 - nature.com
Gene co-expression network analysis (GCNA) can detect alterations in regulatory activities
in case/control comparisons. We propose a framework to detect novel genes and networks …

Constructing cancer patient-specific and group-specific gene networks with multi-omics data

W Lee, DS Huang, K Han - BMC medical genomics, 2020 - Springer
Background Cancer is a complex and heterogeneous disease with many possible genetic
and environmental causes. The same treatment for patients of the same cancer type often …

Risk analysis of colorectal cancer incidence by gene expression analysis

WC Shangkuan, HC Lin, YT Chang, CE Jian, HC Fan… - PeerJ, 2017 - peerj.com
Background. Colorectal cancer (CRC) is one of the leading cancers worldwide. Several
studies have performed microarray data analyses for cancer classification and prognostic …

MLF1 interacting protein: a potential gene therapy target for human prostate cancer?

L Zhang, G Ji, Y Shao, S Qiao, Y Jing, R Qin, H Sun… - Medical Oncology, 2015 - Springer
Here, we investigated the role of one gene that has been previously associated with human
prostate carcinoma cells—myelodysplasia/myeloid leukemia factor 1 interacting protein …

A comparative evaluation of data-merging and meta-analysis methods for reconstructing gene-gene interactions

V Lagani, AD Karozou, D Gomez-Cabrero… - BMC …, 2016 - Springer
Background We address the problem of integratively analyzing multiple gene expression,
microarray datasets in order to reconstruct gene-gene interaction networks. Integrating …

Demystifying DPP III Catalyzed Peptide Hydrolysis—Computational Study of the Complete Catalytic Cycle of Human DPP III Catalyzed Tynorphin Hydrolysis

A Tomić, S Tomić - International journal of molecular sciences, 2022 - mdpi.com
Dipeptidyl peptides III (DPP III) is a dual-domain zinc exopeptidase that hydrolyzes peptides
of varying sequence and size. Despite attempts to elucidate and narrow down the broad …

Neuropeptides, substrates and inhibitors of human dipeptidyl peptidase III, experimental and computational study—A new substrate identified

Z Karačić, F Šupljika, A Tomić, L Brkljačić… - International journal of …, 2022 - Elsevier
Abstract Dipeptidyl peptidase III (DPP III) is a cytosolic, two-domain zinc-exopeptidase. It is
widely distributed in mammalian tissues, where it's involved in the final steps of normal …