Extracellular vesicles as biomarkers in cardiovascular disease; chances and risks

A Dickhout, RR Koenen - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
The field of extracellular vesicles (EV) is rapidly expanding, also within cardiovascular
diseases. Besides their exciting roles in cell-to-cell communication, EV have the potential to …

A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum

K Brennan, K Martin, SP FitzGerald, J O'sullivan… - Scientific reports, 2020 - nature.com
Extracellular vesicles (EVs) are nano-sized vesicles containing nucleic acid and protein
cargo that are released from a multitude of cell types and have gained significant interest as …

Extracellular vesicle measurements with nanoparticle tracking analysis–An accuracy and repeatability comparison between NanoSight NS300 and ZetaView

D Bachurski, M Schuldner, PH Nguyen… - Journal of …, 2019 - Taylor & Francis
The expanding field of extracellular vesicle (EV) research needs reproducible and accurate
methods to characterize single EVs. Nanoparticle Tracking Analysis (NTA) is commonly …

Extracellular vesicles in vascular remodeling

C Ye, F Zheng, N Wu, G Zhu, X Li - Acta Pharmacologica Sinica, 2022 - nature.com
Vascular remodeling contributes to the development of a variety of vascular diseases
including hypertension and atherosclerosis. Phenotypic transformation of vascular cells …

Multiparametric analysis of circulating exosomes and other small extracellular vesicles by advanced imaging flow cytometry

S Mastoridis, GM Bertolino, G Whitehouse… - Frontiers in …, 2018 - frontiersin.org
Extracellular vesicles (EVs) are responsible for a multitude of physiological functions,
including immunomodulation. A heterogenous mixture of small EV (sEV) subsets, including …

A mitochondrial NADPH-cholesterol axis regulates extracellular vesicle biogenesis to support hematopoietic stem cell fate

M Bonora, C Morganti, N van Gastel, K Ito, E Calura… - Cell Stem Cell, 2024 - cell.com
Mitochondrial fatty acid oxidation (FAO) is essential for hematopoietic stem cell (HSC) self-
renewal; however, the mechanism by which mitochondrial metabolism controls HSC fate …

Characterization of diffusing sub-10 nm nano-objects using single anti-resonant element optical fibers

T Wieduwilt, R Förster, M Nissen, J Kobelke… - Nature …, 2023 - nature.com
Accurate characterization of diffusing nanoscale species is increasingly important for
revealing processes at the nanoscale, with fiber-assisted nanoparticle-tracking-analysis …

In vitro dissolution considerations associated with nano drug delivery systems

R Gupta, Y Chen, H Xie - Wiley Interdisciplinary Reviews …, 2021 - Wiley Online Library
Nano drug delivery systems (NDDS) offer promising solution for the translation of future
nanomedicines. As bioavailability and therapeutic outcomes can be improved by altering the …

Composition, isolation, identification and function of adipose tissue-derived exosomes

R Zhao, T Zhao, Z He, R Cai, W Pang - Adipocyte, 2021 - Taylor & Francis
Exosomes are nano-sized extracellular vesicles (30–160 nm diameter) with lipid bilayer
membrane secrete by various cells that mediate the communication between cells and …

Soluble HLA-G (sHLA-G) measurement might be useful as an early diagnostic biomarker and screening test for gastric cancer

LV Mejía-Guarnizo, PS Monroy-Camacho… - Scientific Reports, 2023 - nature.com
Gastric cancer (GC) is the fifth most frequent malignancy worldwide and has a high mortality
rate related to late diagnosis. Although the gold standard for the GC diagnosis is endoscopy …