Abnormal intracellular protein aggregates comprise a key characteristic in most
neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and …

Frontotemporal lobar degeneration (FTLD) is a heterogeneous group of disorders
characterized by disturbances of behavior and personality and different types of language …

Loss-of-function mutations in the progranulin gene are a common cause of familial
frontotemporal dementia (FTD). The purpose of this review is to summarize the role of …

Alzheimer's disease (AD) is the most common form of dementia, most prevalent in the
elderly population and has a significant impact on individuals and their family as well as the …

[Frontiers in Bioscience S3, 252-266, January 1, 2011] 252 Inflammation and oxidative damage
in Alzheimer's disease: friend or f Page 1 [Frontiers in Bioscience S3, 252-266, January 1 …

RNA processing is a tightly regulated, highly complex pathway which includes RNA
transcription, pre-mRNA splicing, editing, transportation, translation, and degradation of …

The purpose of this meta-analysis was to investigate the association between progranulin
polymorphism rs5848 and risk of the neurodegenerative diseases frontotemporal lobar …

Loss-of-function mutations in the multifunctional growth factor progranulin (GRN) cause
frontotemporal lobar degeneration (FTLD) with TDP-43 protein accumulation. Nuclear TDP …

The term frontotemporal lobar degeneration (FTLD) describes a spectrum of
neurodegenerative disorders associated with deposition of misfolded proteins in the frontal …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, whereas
frontotemporal lobar degeneration (FTLD) is the most frequent neurodegenerative disorder …