A census of human RNA-binding proteins

S Gerstberger, M Hafner, T Tuschl - Nature Reviews Genetics, 2014 - nature.com
Post-transcriptional gene regulation (PTGR) concerns processes involved in the maturation,
transport, stability and translation of coding and non-coding RNAs. RNA-binding proteins …

RNA–protein interactions: disorder, moonlighting and junk contribute to eukaryotic complexity

A Balcerak, A Trebinska-Stryjewska… - Open …, 2019 - royalsocietypublishing.org
RNA–protein interactions are crucial for most biological processes in all organisms.
However, it appears that the complexity of RNA-based regulation increases with the …

Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction

R Zheng, K Zhang, S Tan, F Gao, Y Zhang, W Xu… - Molecular cancer, 2022 - Springer
Background Exosomes have emerged as vital biomarkers of multiple cancers and contain
abundant circular RNAs (circRNAs). However, the potential for exosomal circRNAs to be …

RNA structure drives interaction with proteins

N Sanchez de Groot, A Armaos… - Nature …, 2019 - nature.com
The combination of high-throughput sequencing and in vivo crosslinking approaches leads
to the progressive uncovering of the complex interdependence between cellular …

catRAPID omics v2.0: going deeper and wider in the prediction of protein–RNA interactions

A Armaos, A Colantoni, G Proietti, J Rupert… - Nucleic Acids …, 2021 - academic.oup.com
Prediction of protein–RNA interactions is important to understand post-transcriptional events
taking place in the cell. Here we introduce cat RAPID omics v2. 0, an update of our web …

Advances in the characterization of RNA‐binding proteins

D Marchese, NS de Groot… - Wiley …, 2016 - Wiley Online Library
From transcription, to transport, storage, and translation, RNA depends on association with
different RNA‐binding proteins (RBPs). Methods based on next‐generation sequencing and …

RNA-binding and prion domains: the Yin and Yang of phase separation

NL Gotor, A Armaos, G Calloni… - Nucleic acids …, 2020 - academic.oup.com
Proteins and RNAs assemble in membrane-less organelles that organize intracellular
spaces and regulate biochemical reactions. The ability of proteins and RNAs to form …

Prediction of protein-RNA interactions from single-cell transcriptomic data

J Fiorentino, A Armaos, A Colantoni… - Nucleic Acids …, 2024 - academic.oup.com
Proteins are crucial in regulating every aspect of RNA life, yet understanding their
interactions with coding and noncoding RNAs remains limited. Experimental studies are …

RNA‐protein interactions: Central players in coordination of regulatory networks

A Armaos, E Zacco, N Sanchez de Groot… - …, 2021 - Wiley Online Library
Abstract Changes in the abundance of protein and RNA molecules can impair the formation
of complexes in the cell leading to toxicity and death. Here we exploit the information …

Discovering the 3′ UTR-mediated regulation of alpha-synuclein

D Marchese, T Botta-Orfila, D Cirillo… - Nucleic Acids …, 2017 - academic.oup.com
Recent evidence indicates a link between Parkinson's Disease (PD) and the expression of a-
synuclein (SNCA) isoforms with different 3′ untranslated regions (3′ UTRs). Yet, the post …