The potential relevance of long non-coding RNAs in colorectal cancer pathogenesis and treatment: A review focus on signaling pathways

AS Doghish, MB Zaki, MG Eldeib, AF Radwan… - … -Research and Practice, 2023 - Elsevier
Colorectal cancer (CRC) is one of the most frequent cancers in incidence and mortality.
Despite advances in cancer biology, molecular genetics, and targeted treatments, CRC …

Harnessing the power of miRNAs: the molecular architects of asthma pathogenesis and potential targets for therapeutic innovation

TM Al-Noshokaty, D Fathi, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Asthma is a chronic non-communicable respiratory disease that is characterized by airway
inflammation and hyperreactivity. Defective functions of airway smooth muscle and …

Unraveling the role of miRNAs in the diagnosis, progression, and drug resistance of oral cancer

AS Doghish, SS Elshaer, D Fathi, NI Rizk… - … -Research and Practice, 2023 - Elsevier
Oral cancer (OC) is a widely observed neoplasm on a global scale. Over time, there has
been an increase in both its fatality and incidence rates. Oral cancer metastasis is a complex …

REGULATORY ROLES OF microRNAs IN MODULATING MITOCHONDRIAL DYNAMICS, AMYLOID BETA FIBRILLATION, MICROGLIAL ACTIVATION, AND …

M Sharma, AK Tanwar, PK Purohit, P Pal… - Neuroscience & …, 2024 - Elsevier
Alzheimer's Disease (AD) remains a formidable challenge due to its complex pathology,
notably involving mitochondrial dysfunction and dysregulated microRNA (miRNA) signaling …

[HTML][HTML] Mesenchymal Stem Cells from Familial Alzheimer's Patients Express MicroRNA Differently

LJ Rochín-Hernández, LS Rochín-Hernández… - International Journal of …, 2024 - mdpi.com
Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the predominant
form of dementia globally. No reliable diagnostic, predictive techniques, or curative …

Beyond CSF and Neuroimaging Assessment: Evaluating Plasma miR-145-5p as a Potential Biomarker for Mild Cognitive Impairment and Alzheimer's Disease

Q Wen, MMJ Wittens, S Engelborghs… - ACS Chemical …, 2024 - ACS Publications
Alzheimer's disease (AD) is the most common cause of dementia. New strategies for the
early detection of MCI and sporadic AD are crucial for developing effective treatment …

The emerging role of miRNAs in myocardial infarction: From molecular signatures to therapeutic targets

OA Mohammed, M Alghamdi, J Alfaifi… - … -Research and Practice, 2024 - Elsevier
Globally, myocardial infarction (MI) and other cardiovascular illnesses have long been
considered the top killers. Heart failure and mortality are the results of myocardial apoptosis …

miRNAs as modulators of neuroinflammation and excitotoxicity: Implications for stroke therapeutics

MS Elballal, OA Mohammed, MB Zaki… - … -Research and Practice, 2024 - Elsevier
Stroke is a widespread neurological disorder associated with physical disabilities, mortality,
and economic burden. In recent decades, substantial progress has been achieved in …

The potential role of miRNAs in the pathogenesis of schizophrenia-A focus on signaling pathways interplay

MB Zaki, AI Abulsoud, A Ashraf… - … -Research and Practice, 2024 - Elsevier
Abstract microRNAs (miRNAs) play a crucial role in brain growth and function. Hence,
research on miRNA has the potential to reveal much about the etiology of neuropsychiatric …

Unveiling the regulatory role of miRNAs in stroke pathophysiology and diagnosis

MA Abdel-Reheim, Y Nomier, MB Zaki… - … -Research and Practice, 2024 - Elsevier
Stroke, a major global cause of mortality, leads to a range of problems for those who survive.
Besides its brutal events, stroke also tends to have a characteristic of recurrence, making it a …