Nitric oxide (NO) is a versatile molecule that plays key roles in the development and survival
of mammalian species by endowing brain neuronal networks with the ability to make …

Nitric oxide (NO)-sensitive soluble guanylyl cyclase (sGC), an enzyme that catalyzes the
conversion of guanosine-5′-triphosphate (GTP) to cyclic guanosine-3′, 5 …

The nitric oxide (NO) signaling pathway in hypothalamic neurons plays a key role in the
regulation of the secretion of gonadotropin-releasing hormone (GnRH), which is crucial for …

Neuronal hyperexcitability in the central auditory pathway linked to reduced inhibitory
activity is associated with numerous forms of hearing loss, including noise damage, age …

Noise exposure is an important cause of acquired hearing loss. Studies have found that
noise exposure causes dysregulated redox homeostasis in cochlear tissue, which has been …

Cyclic GMP regulates multiple cell types and functions of the cardiovascular system. This
review summarizes the effects of cGMP on the growth and survival of vascular smooth …

cGMP is an important signalling molecule in humans. Fluorescent cGMP biosensors have
emerged as powerful tools for the sensitive analysis of cGMP pathways at the single‐cell …

Nitric oxide (NO) is of fundamental importance in regulating immune, cardiovascular,
reproductive, neuromuscular, and nervous system function. It is rapidly synthesized and …

Oxidative stress is a major contributor to noise-induced hearing loss, the most common
cause of hearing loss among military personnel and young adults. HK-2 is a potent, orally …

The second messenger cyclic guanosine monophosphate (cGMP) is an important regulator
of human (patho-) physiology and has emerged as an attractive drug target. Currently, cGMP …