Intensified downstream processing of monoclonal antibodies using membrane technology

S Nadar, G Shooter, B Somasundaram… - Biotechnology …, 2021 - Wiley Online Library
The need to intensify downstream processing of monoclonal antibodies to complement the
advances in upstream productivity has led to increased attention toward implementing …

Applications of cryostructures in the chromatographic separation of biomacromolecules

N Babanejad, K Mfoafo, E Zhang, Y Omidi… - … of Chromatography A, 2022 - Elsevier
Macroporous-interconnected cryostructures are prepared via cryoprocess approaches,
where polymerization, crosslinking-polymerization, or even chain aggregation is primarily …

Molecular imprinting based composite cryogel membranes for purification of anti-hepatitis B surface antibody by fast protein liquid chromatography

S Asliyuce, L Uzun, AY Rad, S Unal, R Say… - … of Chromatography B, 2012 - Elsevier
In the present study, we have focused our attention to prepare molecular imprinted
composite cryogel membranes for purification of hepatitis B surface antibody (anti-HBs) by …

Molecularly imprinted poly (N-isopropylacrylamide) thermosensitive based cryogel for immunoglobulin G purification

I Perçin, N Idil, A Denizli - Process biochemistry, 2019 - Elsevier
It was aimed to prepare immunoglobulin G (IgG) imprinted thermosensitive p (NIPA-
MAH)/IgG-MIP monolithic cryogel for IgG purification. NIPA and MAH was selected as …

Surface imprinting approach for preparing specific adsorbent for IgG separation

Y Saylan, R Üzek, L Uzun, A Denizli - Journal of Biomaterials …, 2014 - Taylor & Francis
In this study, we focused our attention on preparing of a new adsorbent for specific
separation of immunoglobulin G (IgG). In this respect, we applied core–shell surface …

Purification of antibodies by affinity chromatography

A Denizli - Hacettepe Journal of Biology and Chemistry, 2011 - dergipark.org.tr
Antibodies are becoming a dominant protein class for various human therapeutical
applications and they represent the largest number of molecules in clinical trials today …

Affinity composite cryogel discs functionalized with Reactive Red 120 and Green HE 4BD dye ligands: Application on the separation of human immunoglobulin G …

S Huseynli, G Baydemir, E Sarı, A Elkak… - Materials Science and …, 2015 - Elsevier
Naturally produced by the human immune system, immunoglobulin nowadays is widely
used for in vivo and in vitro purposes. The increased needs for pure immunoglobulin have …

Synthesis of L-lysine imprinted cryogels for immunoglobulin G adsorption

S Çulha, C Armutcu, L Uzun, S Şenel… - Materials Science and …, 2015 - Elsevier
Abstract l-Lysine imprinted poly (2-hydroxyethyl methacrylate-co-N-methacryloyl-l-aspartic
acid)[P (HEMA-co-MAAsp)] cryogels were synthesized and characterized with Fourier …

Aspartic acid incorporated monolithic columns for affinity glycoprotein purification

C Armutcu, N Bereli, E Bayram, L Uzun, R Say… - Colloids and Surfaces B …, 2014 - Elsevier
Novel aspartic acid incorporated monolithic columns were prepared to efficiently affinity
purify immunoglobulin G (IgG) from human plasma. The monolithic columns were …

Bio-functionalized nanofibrous membranes as a hybrid platform for selective antibody recognition and capturing

J Zhu, G Sun - RSC Advances, 2015 - pubs.rsc.org
Poly (vinyl alcohol-co-ethylene)(PVA-co-PE) is attractive for a variety of bio-applications due
to its intrinsic hydrophilicity and ease of functionalization. The successful preparation of PVA …