Follicular fluid: a powerful tool for the understanding and diagnosis of polycystic ovary syndrome

AT Brinca, AC Ramalhinho, Â Sousa, AH Oliani… - Biomedicines, 2022 - mdpi.com
Polycystic ovary syndrome (PCOS) represents one of the leading causes of anovulatory
infertility and affects 5% to 20% of women worldwide. Until today, both the subsequent …

The role of female reproductive fluid in sperm competition

C Gasparini, A Pilastro… - … Transactions of the …, 2020 - royalsocietypublishing.org
The role of non-gametic components of the ejaculate (seminal fluid) in fertility and sperm
competitiveness is now well established. Surprisingly, however, we know far less about …

Recent advances in lectin-based affinity sorbents for protein glycosylation studies

A Goumenou, N Delaunay, V Pichon - Frontiers in Molecular …, 2021 - frontiersin.org
Glycosylation is one of the most significant post-translational modifications occurring to
proteins, since it affects some of their basic properties, such as their half-life or biological …

[HTML][HTML] Pathogenetic analysis of polycystic ovary syndrome from the perspective of omics

CZ Pei, L Jin, KH Baek - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disease,
involving multiple genes, multiple pathways, and complex hormone secretion processes …

An integrated in silico analysis highlighted angiogenesis regulating miRNA-mRNA network in PCOS pathophysiology

K Patil, S Joseph, J Shah, S Mukherjee - Journal of Assisted Reproduction …, 2022 - Springer
Background Polycystic ovary syndrome (PCOS) is a heterogeneous endocrinopathy and a
leading cause of anovulatory infertility. Angiogenesis is vital for ovarian folliculogenesis. The …

Alteration in angiogenic potential of granulosa-lutein cells and follicular fluid contributes to luteal defects in polycystic ovary syndrome

K Patil, I Hinduja, S Mukherjee - Human Reproduction, 2021 - academic.oup.com
STUDY QUESTION Is angiogenic potential of follicular fluid (FF) and granulosa-lutein cells
(GLCs) altered in polycystic ovary syndrome (PCOS) and does it play a role in corpus luteum …

Disturbed Follicular Microenvironment in Polycystic Ovary Syndrome: Relationship to Oocyte Quality and Infertility

M Dai, L Hong, T Yin, S Liu - Endocrinology, 2024 - academic.oup.com
Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with
infertility and poor reproductive outcomes. The follicular fluid (FF) microenvironment plays a …

Multi-omics insights and therapeutic implications in polycystic ovary syndrome: a review

A Babu, G Ramanathan - Functional & Integrative Genomics, 2023 - Springer
Polycystic ovary syndrome (PCOS) is a common gynecological disease that causes adverse
effects in women in their reproductive phase. Nonetheless, the molecular mechanisms …

Transcriptomic profile of GLCs of PCOS women highlights metabolic dysregulation as a plausible contributor to PCOS pathophysiology

K Patil, A Naigaonkar, I Hinduja, S Mukherjee - Reproductive Biology, 2023 - Elsevier
Polycystic ovary syndrome (PCOS) is a complex heterogeneous disorder with reproductive
and metabolic consequences whose aetiology is still elusive. To understand the cellular …

Glycomic and glycoproteomic techniques in neurodegenerative disorders and neurotrauma: towards personalized markers

F Kobeissy, A Kobaisi, W Peng, C Barsa, M Goli… - Cells, 2022 - mdpi.com
The proteome represents all the proteins expressed by a genome, a cell, a tissue, or an
organism at any given time under defined physiological or pathological circumstances …