Apolipoprotein E (ApoE) is of great interest due to its role as a cholesterol/lipid transporter in
the central nervous system (CNS) and as the most influential genetic risk factor for Alzheimer …

Host defense antimicrobial peptides are key components of human innate immunity that
plays an indispensible role in human health. While there are multiple copies of cathelicidin …

An antimicrobial peptide database (APD) has been established based on an extensive
literature search. It contains detailed information for 525 peptides (498 antibacterial, 155 …

To understand the structure and activity relationship of human LL-37, a series of peptide
fragments was designed. The N-terminal fragment, LL-37 (1− 12), was not active, while the …

Biofouling is the undesirable accumulation of organisms such as bacteria, fungi, and
barnacles on surfaces. It is a serious problem in many areas of our lives including health …

Human apolipoprotein (apo) AI has been the subject of intense investigation because of its
well-documented anti-atherogenic properties. About 70% of the protein found in high density …

Antimicrobial peptides (AMPs) represent a class of natural peptides that form a part of the
innate immune system, and this kind of 'nature's antibiotics' is quite promising for solving the …

A detailed analysis of backbone amide NH chemical shift temperature gradients (Δδ/Δ T
values) for proteins and highly cross-linked peptides reveals that hydrogen-bonded …

Short antimicrobial peptides are essential to keep us healthy and their lasting potency can
inspire the design of new types of antibiotics. This study reports the design of a family of …

Human apolipoprotein E (apoE) is composed of an N-terminal (NT) domain (residues 1–
191) that bears low-density lipoprotein receptor-binding sites, and a C-terminal (CT) domain …