MicroRNAs as the actors in the atherosclerosis scenario

F Hajibabaie, S Kouhpayeh, M Mirian… - Journal of physiology …, 2020 - Springer
Atherosclerosis is considered as the most common cardiovascular disease and a leading
cause of global mortality, which develops through consecutive steps. Various cellular and …

Exploring regulatory mechanisms on miRNAs and their implications in inflammation-related diseases

E Nalbant, YZ Akkaya-Ulum - Clinical and experimental medicine, 2024 - Springer
This comprehensive exploration delves into the pivotal role of microRNAs (miRNAs) within
the intricate tapestry of cellular regulation. As potent orchestrators of gene expression …

An update on the cell-free DNA-derived methylome as a non-invasive biomarker for coronary artery disease

M Dash, B Mahajan, GM Dar, P Sahu… - The International Journal …, 2024 - Elsevier
Cardiovascular diseases are the foremost contributor to global mortality, presenting a
complex etiology and an expanding array of risk factors. Coronary artery disease …

The role of DNA methylation in coronary artery disease

L Duan, J Hu, X Xiong, Y Liu, J Wang - Gene, 2018 - Elsevier
Epigenetic studies have identified DNA methylation in coronary artery disease (CAD). How
the critical genes interact at the cellular level to cause CAD is still unknown. The discovery of …

Role of microRNA in development of instability of atherosclerotic plaques

IA Koroleva, MS Nazarenko, AN Kucher - Biochemistry (Moscow), 2017 - Springer
MicroRNAs are small noncoding single-stranded RNAs that regulate gene expression.
Today, we see an increasing number of studies highlighting the important role of microRNAs …

Identification of novel hyper-or hypomethylated CpG sites and genes associated with atherosclerotic plaque using an epigenome-wide association study

Y Yamada, H Horibe, M Oguri… - International …, 2018 - spandidos-publications.com
DNA methylation is an important epigenetic modification that has been implicated in the
pathogenesis of atherosclerosis. Although previous studies have identified various CpG …

Epigenetics of Cardiomyopathy: Histone Modifications and DNA Methylation

AN Kucher, MS Nazarenko - Russian Journal of Genetics, 2023 - Springer
Cardiomyopathies are an actively investigated clinically and genetically heterogeneous
group of myocardial pathologies. At present, it is acknowledged that along with genetic …

Integrated Analysis of Gene Expression and Methylation Data to Identify Potential Biomarkers Related to Atherosclerosis Onset

X Li, X Dong, W Lu, K Yang, X Li - Oxidative Medicine and …, 2022 - Wiley Online Library
Atherosclerosis is a kind of chronic inflammatory cardiovascular disease. Epigenetic
regulation plays a crucial role in atherosclerosis. Our study was aimed at finding potential …

Methylation of Regulatory Regions of DNA Repair Genes in Carotid Atherosclerosis

NP Babushkina, AA Zarubin, IA Koroleva… - Molecular Biology, 2023 - Springer
The status of DNA methylation in the human genome changes during the pathogenesis of
common diseases and acts as a predictor of life expectancy. Therefore, it is of interest to …

DNA Methylation in Aortic Aneurysms of Different Localizations

AN Kucher, SA Shipulina, IA Goncharova… - Russian Journal of …, 2024 - Springer
Aortic aneurysm (AA) is a life-threatening condition, and aortic rupture that is the
complication of AA in the absence of emergency surgery leads to death. Genetic (more often …