Polyunsaturated fatty acids (PUFAs) are structural components of membrane phospholipids,
and influence cellular function via effects on membrane properties, and also by acting as a …

Interactions between the immune and nervous systems are of central importance in
neuropathic pain, a common and debilitating form of chronic pain caused by a lesion or …

Specialized pro-resolving mediators (SPMs), including resolvins, protectins, and maresins,
are endogenous lipid mediators that are synthesized from omega-3 polyunsaturated fatty …

This review is a synopsis of the main points from the opening presentation by the authors in
the Resolution of Inflammation session at the 8th European Workshop on Lipid Mediators …

Inflammation is known to cause pain, and pain is of one of the cardinal signs of
inflammation. Mounting evidence suggests that acute inflammation also resolves pain …

Pain imposes a significant urden on patients, affecting them physically, psychologically, and
economically. Despite numerous studies on the pathogenesis of pain, its clinical …

Macrophages release soluble mediators following efferocytic clearance of apoptotic cells to
facilitate intercellular communication and promote the resolution of inflammation. However …

Sepsis is a systemic inflammatory response syndrome caused by infection, following with
acute injury to multiple organs. Sepsis-induced acute kidney injury (AKI) is currently …

G protein–coupled receptor 37-like 1 (GPR37L1) is an orphan GPCR with largely unknown
functions. Here, we report that Gpr37l1/GRP37L1 ranks among the most highly expressed …

Inhibitory GABA-ergic neurotransmission is fundamental for the adult vertebrate central
nervous system and requires low chloride concentration in neurons, maintained by KCC2, a …