Dietary carbohydrates and fatty liver disease: de novo lipogenesis

S Chiu, K Mulligan, JM Schwarz - Current Opinion in Clinical …, 2018 - journals.lww.com
Dietary carbohydrates and fatty liver disease: de novo lipog... : Current Opinion in Clinical
Nutrition & Metabolic Care Dietary carbohydrates and fatty liver disease: de novo lipogenesis …

RGC-32 and diseases: the first 20 years

SI Vlaicu, A Tatomir, F Anselmo, D Boodhoo… - Immunologic …, 2019 - Springer
The response gene to complement (RGC)-32 acts as a cell cycle regulator and mediator of
TGF-β effects. However, recent studies have revealed other functions for RGC-32 in diverse …

RGC-32 (response gene to complement 32) deficiency protects endothelial cells from inflammation and attenuates atherosclerosis

XB Cui, JN Luan, K Dong, S Chen, Y Wang… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—The objective of this study is to determine the role and underlying mechanisms of
RGC-32 (response gene to complement 32 protein) in atherogenesis. Approach and Results …

Regulator of cell cycle protein (RGCC/RGC-32) protects against pulmonary fibrosis

IG Luzina, V Rus, V Lockatell, JP Courneya… - American journal of …, 2022 - atsjournals.org
Some previous studies in tissue fibrosis have suggested a profibrotic contribution from
elevated expression of a protein termed either RGCC (regulator of cell cycle) or RGC-32 …

Diclofenac Disrupts the Circadian Clock and through Complex Cross-Talks Aggravates Immune-Mediated Liver Injury—A Repeated Dose Study in Minipigs for 28 …

S Selvaraj, JH Oh, S Yoon, J Borlak - International Journal of Molecular …, 2023 - mdpi.com
Diclofenac effectively reduces pain and inflammation; however, its use is associated with
hepato-and nephrotoxicity. To delineate mechanisms of injury, we investigated a clinically …

RGC-32 mediates proinflammatory and profibrotic pathways in immune-mediated kidney disease

A Tatomir, S Vlaicu, V Nguyen, IG Luzina, SP Atamas… - Clinical …, 2024 - Elsevier
Systemic lupus erythematosus is an autoimmune disease that results in immune-mediated
damage to kidneys and other organs. We investigated the role of response gene to …

ADAR1 deficiency protects against high-fat diet-induced obesity and insulin resistance in mice

XB Cui, J Fei, S Chen, GL Edwards… - American Journal of …, 2021 - journals.physiology.org
Obesity is an important independent risk factor for type 2 diabetes, cardiovascular diseases,
and many other chronic diseases. The objective of this study was to determine the role of …

Response gene to complement 32 in vascular diseases

XB Cui, SY Chen - Frontiers in cardiovascular medicine, 2018 - frontiersin.org
Response gene to complement 32 (RGC32) is a protein that was identified in rat
oligodendrocytes after complement activation. It is expressed in most of the organs and …

Response gene to complement 32 maintains blood pressure homeostasis by regulating α-adrenergic receptor expression

JM Tang, N Shi, K Dong, SA Brown… - Circulation …, 2018 - Am Heart Assoc
Rationale: Hypertension prevalence is much higher among children and adolescents with
low birth weight and greater postnatal weight gain than in individuals with normal birth …

RGC32 induces epithelial-mesenchymal transition by activating the Smad/Sip1 signaling pathway in CRC

XY Wang, SN Li, HF Zhu, ZY Hu, Y Zhong, CS Gu… - Scientific Reports, 2017 - nature.com
Response gene to complement 32 (RGC32) is a transcription factor that regulates the
expression of multiple genes involved in cell growth, viability and tissue-specific …