Roles of clock genes in the pathogenesis of Parkinson's disease

AD Shkodina, SC Tan, MM Hasan… - Ageing Research …, 2022 - Elsevier
Parkinson's disease (PD) is a common motor disorder that has become increasingly
prevalent in the ageing population. Recent works have suggested that circadian rhythms …

The phenomenology of Parkinson's disease

CW Hess, M Hallett - Seminars in neurology, 2017 - thieme-connect.com
The motor symptoms of Parkinson's disease are not limited to the cardinal symptoms of
bradykinesia, rigidity, and resting tremor, but also include a variety of interrelated motor …

Variability of movement disorders: the influence of sensation, action, cognition, and emotions

R Berlot, JC Rothwell, KP Bhatia… - Movement …, 2021 - Wiley Online Library
Patients with movement disorders experience fluctuations unrelated to disease progression
or treatment. Extrinsic factors that contribute to the variable expression of movement …

Stress and cortisol in Parkinson's disease

DJ van Wamelen, YM Wan, KR Chaudhuri… - International Review of …, 2020 - Elsevier
Stress is ubiquitous with many factors contributing to its effects, including psychological
responses and associated biological factors, including cortisol related physiological …

Characterization of nonmotor behavioral impairments and their neurochemical mechanisms in the MitoPark mouse model of progressive neurodegeneration in …

MR Langley, S Ghaisas, BN Palanisamy, M Ay… - Experimental …, 2021 - Elsevier
Mitochondrial dysfunction has been implicated as a key player in the pathogenesis of
Parkinson's disease (PD). The MitoPark mouse, a transgenic mitochondrial impairment …

[HTML][HTML] Unexpected dual task benefits on cycling in Parkinson disease and healthy adults: A neuro-behavioral model

LJP Altmann, E Stegemöller, AA Hazamy, JP Wilson… - PloS one, 2015 - journals.plos.org
Background When performing two tasks at once, a dual task, performance on one or both
tasks typically suffers. People with Parkinson's disease (PD) usually experience larger dual …

[HTML][HTML] Los estudios del comportamiento humano en la construcción de la neurociencia educacional

MA Bacigalupe - Inter disciplina, 2020 - scielo.org.mx
En el presente artículo nos proponemos discutir la construcción de la neurociencia
educacional y sus relaciones con algunos estudios del comportamiento humano que …

[HTML][HTML] Dopaminergic balance between reward maximization and policy complexity

N Parush, N Tishby, H Bergman - Frontiers in Systems Neuroscience, 2011 - frontiersin.org
Previous reinforcement-learning models of the basal ganglia network have highlighted the
role of dopamine in encoding the mismatch between prediction and reality. Far less attention …

Paradoxical kinesia in Parkinson's disease revisited: anticipation of temporal constraints is critical

M Distler, JCM Schlachetzki, Z Kohl, J Winkler… - Neuropsychologia, 2016 - Elsevier
Slowness of movement, called bradykinesia is the cardinal symptom of Parkinson's disease.
Under distinct but not yet well-defined circumstances, patients with Parkinson's disease are …

Improvements in rate of development and magnitude of force with intense auditory stimuli in patients with Parkinson's disease

A Anzak, H Tan, A Pogosyan… - European Journal of …, 2011 - Wiley Online Library
Patients with Parkinson's disease can show brief but dramatic normalization of motor activity
in highly arousing situations, a phenomenon often termed paradoxical kinesis. We sought to …