Hepatic fibrosis is a dynamic process characterized by the net accumulation of extracellular
matrix resulting from chronic liver injury of any aetiology, including viral infection, alcoholic …

Progressive liver fibrosis, induced by chronic viral and metabolic disorders, leads to more
than one million deaths annually via development of cirrhosis, although no antifibrotic …

Background & Aims Angiocrine signaling by liver sinusoidal endothelial cells (LSECs)
regulates hepatic functions such as growth, metabolic maturation, and regeneration …

Background and aims Liver fibrosis is a wound-healing response that disrupts the liver
architecture and function by replacing functional parenchyma with scar tissue. Recent …

At present, there are no effective antifibrotic drugs for patients with chronic liver disease;
hence, the development of antifibrotic therapies is urgently needed. Here, we performed an …

The hepatic stellate cells (HSCs) localize at the space of Disse in the liver and have multiple
functions. They are identified as the major contributor to hepatic fibrosis. Significant …

The C‐type lectin domain (CTLD) group 14 family of transmembrane glycoproteins consist of
thrombomodulin, CD 93, CLEC 14A and CD 248 (endosialin or tumour endothelial marker …

Background Growing evidence supports a key role for inflammation in the onset and
progression of tendinopathy. However, the effect of the inflammatory infiltrate on tendon cells …

To date, no herpesvirus has been shown to latently persist in fibroblastic cells. Here, we
show that murine cytomegalovirus, a β-herpesvirus, persists for the long term and across …

Abstract CD248/endosialin/TEM1 is a type 1 transmembrane glycoprotein found on the
plasma membrane of activated mesenchymal cells. CD248 functions during embryo …