A materials-science perspective on tackling COVID-19

Z Tang, N Kong, X Zhang, Y Liu, P Hu, S Mou… - Nature Reviews …, 2020 - nature.com
The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in
providing tools and technologies for antiviral research and treatment development. In this …

MicroRNA regulation of RNA virus replication and pathogenesis

DW Trobaugh, WB Klimstra - Trends in molecular medicine, 2017 - cell.com
microRNAs (miRNAs) are non-coding RNAs that regulate many processes within a cell by
manipulating protein levels through direct binding to mRNA and influencing translation …

VirFinder: a novel k-mer based tool for identifying viral sequences from assembled metagenomic data

J Ren, NA Ahlgren, YY Lu, JA Fuhrman, F Sun - Microbiome, 2017 - Springer
Background Identifying viral sequences in mixed metagenomes containing both viral and
host contigs is a critical first step in analyzing the viral component of samples. Current tools …

Identifying viruses from metagenomic data using deep learning

J Ren, K Song, C Deng, NA Ahlgren… - Quantitative …, 2020 - Wiley Online Library
Background The recent development of metagenomic sequencing makes it possible to
massively sequence microbial genomes including viral genomes without the need for …

Extremely high mutation rate of HIV-1 in vivo

JM Cuevas, R Geller, R Garijo, J López-Aldeguer… - PLoS …, 2015 - journals.plos.org
Rates of spontaneous mutation critically determine the genetic diversity and evolution of
RNA viruses. Although these rates have been characterized in vitro and in cell culture …

Global aspects of viral glycosylation

I Bagdonaite, HH Wandall - Glycobiology, 2018 - academic.oup.com
Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …

Nanotechnology and plant viruses: an emerging disease management approach for resistant pathogens

T Farooq, M Adeel, Z He, M Umar, N Shakoor… - ACS …, 2021 - ACS Publications
Phytoviruses are highly destructive plant pathogens, causing significant agricultural losses
due to their genomic diversity, rapid, and dynamic evolution, and the general inadequacy of …

Orally efficacious broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial viruses

JJ Yoon, M Toots, S Lee, ME Lee… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Morbidity and mortality resulting from influenza-like disease are a threat, especially for older
adults. To improve case management, next-generation broad-spectrum antiviral …

An RNA toolbox for cancer immunotherapy

F Pastor, P Berraondo, I Etxeberria… - Nature Reviews Drug …, 2018 - nature.com
Cancer immunotherapy has revolutionized oncology practice. However, current protein and
cell therapy tools used in cancer immunotherapy are far from perfect, and there is room for …

[HTML][HTML] Dietary selenium in adjuvant therapy of viral and bacterial infections

H Steinbrenner, S Al-Quraishy, MA Dkhil… - Advances in …, 2015 - Elsevier
Viral and bacterial infections are often associated with deficiencies in macronutrients and
micronutrients, including the essential trace element selenium. In selenium deficiency …