A materials-science perspective on tackling COVID-19
The ongoing SARS-CoV-2 pandemic highlights the importance of materials science in
providing tools and technologies for antiviral research and treatment development. In this …
providing tools and technologies for antiviral research and treatment development. In this …
MicroRNA regulation of RNA virus replication and pathogenesis
DW Trobaugh, WB Klimstra - Trends in molecular medicine, 2017 - cell.com
microRNAs (miRNAs) are non-coding RNAs that regulate many processes within a cell by
manipulating protein levels through direct binding to mRNA and influencing translation …
manipulating protein levels through direct binding to mRNA and influencing translation …
VirFinder: a novel k-mer based tool for identifying viral sequences from assembled metagenomic data
Background Identifying viral sequences in mixed metagenomes containing both viral and
host contigs is a critical first step in analyzing the viral component of samples. Current tools …
host contigs is a critical first step in analyzing the viral component of samples. Current tools …
Identifying viruses from metagenomic data using deep learning
J Ren, K Song, C Deng, NA Ahlgren… - Quantitative …, 2020 - Wiley Online Library
Background The recent development of metagenomic sequencing makes it possible to
massively sequence microbial genomes including viral genomes without the need for …
massively sequence microbial genomes including viral genomes without the need for …
Extremely high mutation rate of HIV-1 in vivo
Rates of spontaneous mutation critically determine the genetic diversity and evolution of
RNA viruses. Although these rates have been characterized in vitro and in cell culture …
RNA viruses. Although these rates have been characterized in vitro and in cell culture …
Global aspects of viral glycosylation
I Bagdonaite, HH Wandall - Glycobiology, 2018 - academic.oup.com
Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …
infections of different severity, ranging from no or very few symptoms to lethal disease as …
Nanotechnology and plant viruses: an emerging disease management approach for resistant pathogens
Phytoviruses are highly destructive plant pathogens, causing significant agricultural losses
due to their genomic diversity, rapid, and dynamic evolution, and the general inadequacy of …
due to their genomic diversity, rapid, and dynamic evolution, and the general inadequacy of …
Orally efficacious broad-spectrum ribonucleoside analog inhibitor of influenza and respiratory syncytial viruses
JJ Yoon, M Toots, S Lee, ME Lee… - Antimicrobial agents …, 2018 - Am Soc Microbiol
Morbidity and mortality resulting from influenza-like disease are a threat, especially for older
adults. To improve case management, next-generation broad-spectrum antiviral …
adults. To improve case management, next-generation broad-spectrum antiviral …
An RNA toolbox for cancer immunotherapy
Cancer immunotherapy has revolutionized oncology practice. However, current protein and
cell therapy tools used in cancer immunotherapy are far from perfect, and there is room for …
cell therapy tools used in cancer immunotherapy are far from perfect, and there is room for …
[HTML][HTML] Dietary selenium in adjuvant therapy of viral and bacterial infections
H Steinbrenner, S Al-Quraishy, MA Dkhil… - Advances in …, 2015 - Elsevier
Viral and bacterial infections are often associated with deficiencies in macronutrients and
micronutrients, including the essential trace element selenium. In selenium deficiency …
micronutrients, including the essential trace element selenium. In selenium deficiency …