Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus

SS Gonçalves, ACR Souza, A Chowdhary, JF Meis… - Mycoses, 2016 - Wiley Online Library
The significant increase in the use of antifungal agents, both for the treatment of candidiasis
and invasive aspergillosis and as azole fungicides in agricultural crop protection has …

Acquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection

SJ Howard, MC Arendrup - Medical mycology, 2011 - academic.oup.com
Voriconazole is the recommended agent for invasive aspergillosis, with lipid amphotericin B
or caspofungin as second line treatment choices. Being the only agents available in oral …

Current status of antifungal resistance and its impact on clinical practice

L Alcazar‐Fuoli, E Mellado - British journal of haematology, 2014 - Wiley Online Library
Mortality linked to invasive fungal diseases remains very high despite the availability of
novel antifungals and new therapeutic strategies. C andida albicans and A spergillus …

Opportunistic invasive fungal disease in patients with type 2 diabetes mellitus from Southern China: clinical features and associated factors

M Lao, C Li, J Li, D Chen, M Ding… - Journal of diabetes …, 2020 - Wiley Online Library
Aims/Introduction A retrospective study was carried out to investigate the clinical
characteristics and associated factors for invasive fungal disease in patients with type 2 …

Management of invasive infections in diabetes mellitus: A comprehensive review

A Khanam, G Hithamani, J Naveen, SR Pradeep… - Biologics, 2023 - mdpi.com
Patients with diabetes often have more invasive infections, which may lead to an increase in
morbidity. The hyperglycaemic environment promotes immune dysfunction (such as the …

Trends in the prevalence of amphotericin B-resistance (AmBR) among clinical isolates of Aspergillus species

H Fakhim, H Badali, E Dannaoui, M Nasirian… - Journal of Medical …, 2022 - Elsevier
The challenges of the invasive infections caused by the resistant Aspergillus species include
the limited access to antifungals for treatment and high mortality. This study aimed to provide …

Invasive Aspergillosis Due to Aspergillus Section Usti: A Multicenter Retrospective Study

E Glampedakis, S Cassaing, A Fekkar… - Clinical Infectious …, 2021 - academic.oup.com
Background Aspergillus spp. of section Usti (A. ustus) represent a rare cause of invasive
aspergillosis (IA). This multicenter study describes the epidemiology and outcome of A …

Drug-Resistant Aspergillus spp.: A Literature Review of Its Resistance Mechanisms and Its Prevalence in Europe

MA De Francesco - Pathogens, 2023 - mdpi.com
Infections due to the Aspergillus species constitute an important challenge for human health.
Invasive aspergillosis represents a life-threatening disease, mostly in patients with immune …

Interleukin-10 promoter polymorphism as risk factor to develop invasive pulmonary aspergillosis

J Sainz, L Hassan, E Perez, A Romero, A Moratalla… - Immunology letters, 2007 - Elsevier
This present study was undertaken to examine the role of the host response to Aspergillus
fumigatus in the development of clinical symptoms of invasive pulmonary aspergillosis (IPA) …

[HTML][HTML] Aspergillus ustus infections among transplant recipients

AA Panackal, A Imhof, EW Hanley… - Emerging infectious …, 2006 - ncbi.nlm.nih.gov
Aspergillus ustus is a mold that rarely infects humans; only 15 systemic cases have been
reported. We report the first outbreak of invasive infection caused by A. ustus among …