[HTML][HTML] Perturbation of serine enantiomers homeostasis in the striatum of MPTP-lesioned monkeys and mice reflects the extent of dopaminergic midbrain …
Loss of dopaminergic midbrain neurons perturbs l-serine and d-serine homeostasis in the
post-mortem caudate putamen (CPu) of Parkinson's disease (PD) patients. However, it is …
post-mortem caudate putamen (CPu) of Parkinson's disease (PD) patients. However, it is …
Biochemical and cellular studies of three human 3‐phosphoglycerate dehydrogenase variants responsible for pathological reduced L‐serine levels
G Murtas, E Zerbini, V Rabattoni, Z Motta… - …, 2024 - Wiley Online Library
In the brain, the non‐essential amino acid L‐serine is produced through the phosphorylated
pathway (PP) starting from the glycolytic intermediate 3‐phosphoglycerate: among the …
pathway (PP) starting from the glycolytic intermediate 3‐phosphoglycerate: among the …
[HTML][HTML] Effect of l-serine and magnesium ions on the functional properties of human phosphoserine phosphatase and its pathogenetic variants
F Marchesani, VB Comani, S Bruno… - … et Biophysica Acta (BBA …, 2024 - Elsevier
L-Ser supply in the central nervous system of mammals mostly relies on its endogenous
biosynthesis by the phosphorylated pathway (PP). Defects in any of the three enzymes …
biosynthesis by the phosphorylated pathway (PP). Defects in any of the three enzymes …
On the regulation of human D‐aspartate oxidase
V Rabattoni, Z Motta, M Miceli, G Molla… - Protein …, 2023 - Wiley Online Library
The human flavoenzyme D‐aspartate oxidase (hDASPO) controls the level of D‐aspartate in
the brain, a molecule acting as an agonist of NMDA receptors and modulator of AMPA and …
the brain, a molecule acting as an agonist of NMDA receptors and modulator of AMPA and …
Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization
F Marchesani, A Michielon, E Viale, A Bianchera… - Biomolecules, 2023 - mdpi.com
In humans, the phosphorylated pathway (PP) converts the glycolytic intermediate D-3-
phosphoglycerate (3-PG) into L-serine through the enzymes 3-phosphoglycerate …
phosphoglycerate (3-PG) into L-serine through the enzymes 3-phosphoglycerate …
L-serine deficiency: on the properties of the Asn133Ser variant of human phosphoserine phosphatase
The non-essential amino acid L-serine is involved in a number of metabolic pathways and in
the brain its level is largely due to the biosynthesis from the glycolytic intermediate D-3 …
the brain its level is largely due to the biosynthesis from the glycolytic intermediate D-3 …
On the quaternary structure of human D‐3‐phosphoglycerate dehydrogenase
Abstract D‐3‐phosphoglycerate dehydrogenase (PHGDH) catalyzes the NAD+‐dependent
conversion of D‐3‐phospho‐glycerate to 3‐phosphohydroxypyruvate, the first step in the …
conversion of D‐3‐phospho‐glycerate to 3‐phosphohydroxypyruvate, the first step in the …
Molecular landscape of glucose metabolism in glioblastoma and the normal human brain: A narrative review
P Shah, RR Pallavali, DR Guda - Glioma, 2024 - journals.lww.com
Glioblastoma multiforme (GBM) is one of the most aggressive tumors known to occur in the
brain. Metabolism is one of the driving factors enabling the successful proliferation of tumor …
brain. Metabolism is one of the driving factors enabling the successful proliferation of tumor …
[PDF][PDF] Phosphoserine Aminotransferase Pathogenetic Variants in Serine Deficiency Disorders: A Functional Characterization. Biomolecules 2023, 13, 1219
F Marchesani, A Michielon, E Viale, A Bianchera… - 2023 - academia.edu
In humans, the phosphorylated pathway (PP) converts the glycolytic intermediate D-3-
phosphoglycerate (3-PG) into L-serine through the enzymes 3-phosphoglycerate …
phosphoglycerate (3-PG) into L-serine through the enzymes 3-phosphoglycerate …