Advances and highlights in biomarkers of allergic diseases

I Ogulur, Y Pat, O Ardicli, E Barletta, L Cevhertas… - Allergy, 2021 - Wiley Online Library
During the past years, there has been a global outbreak of allergic diseases, presenting a
considerable medical and socioeconomical burden. A large fraction of allergic diseases is …

Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma

H Breiteneder, YQ Peng, I Agache, Z Diamant… - Allergy, 2020 - Wiley Online Library
Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

A compendium answering 150 questions on COVID‐19 and SARS‐CoV‐2

C Riggioni, P Comberiati, M Giovannini, I Agache… - Allergy, 2020 - Wiley Online Library
Abstract In December 2019, China reported the first cases of the coronavirus disease 2019
(COVID‐19). This disease, caused by the severe acute respiratory syndrome–related …

Non‐specific lipid‐transfer proteins: Allergen structure and function, cross‐reactivity, sensitization, and epidemiology

IJ Skypala, R Asero, D Barber, L Cecchi… - Clinical and …, 2021 - Wiley Online Library
Background Discovered and described 40 years ago, non‐specific lipid transfer proteins
(nsLTP) are present in many plant species and play an important role protecting plants from …

Roles of follicular helper and regulatory T cells in allergic diseases and allergen immunotherapy

Y Yao, CL Chen, D Yu, Z Liu - Allergy, 2021 - Wiley Online Library
Allergic diseases are characterized by overactive type 2 immune responses to allergens and
immunoglobulin E (IgE)‐mediated hypersensitivity. Emerging evidence suggests that …

Type 2–polarized memory B cells hold allergen-specific IgE memory

JFE Koenig, NPH Knudsen, A Phelps… - Science Translational …, 2024 - science.org
Allergen-specific immunoglobulin E (IgE) antibodies mediate pathology in diseases such as
allergic rhinitis and food allergy. Memory B cells (MBCs) contribute to circulating IgE by …

Recent developments and highlights in food allergy

T Eiwegger, L Hung, KE San Diego, L O'Mahony… - Allergy, 2019 - Wiley Online Library
The achievement of long‐lasting, safe treatments for food allergy is dependent on the
understanding of the immunological basis of food allergy. Accurate diagnosis is essential for …

The impact of type 2 immunity and allergic diseases in atherosclerosis

N Fernández‐Gallego, R Castillo‐González… - Allergy, 2022 - Wiley Online Library
Allergic diseases are allergen‐induced immunological disorders characterized by the
development of type 2 immunity and IgE responses. The prevalence of allergic diseases has …

Biology and dynamics of B cells in the context of IgE‐mediated food allergy

P Satitsuksanoa, M Daanje, M Akdis, SD Boyd… - Allergy, 2021 - Wiley Online Library
An increasing number of people suffer from IgE‐mediated food allergies. The immunological
mechanisms that cause IgE‐mediated food allergy have been extensively studied. B cells …

IgE plasma cells are transcriptionally and functionally distinct from other isotypes

A Vecchione, JC Devlin, C Tasker… - Science …, 2024 - science.org
Understanding the phenotypic and transcriptional signature of immunoglobulin E (IgE)–
producing cells is fundamental to plasma cell (PC) biology and development of therapeutic …