African natural products with potential antioxidants and hepatoprotectives properties: a review

B Lawal, OK Shittu, FI Oibiokpa, EB Berinyuy… - Clinical …, 2017 - Springer
Free radicals are highly reactive molecules generated during oxidation reactions which in
turn initiate chain reactions resulting to cellular damage. There is substantial evidence …

Models of drug-induced liver injury for evaluation of phytotherapeutics and other natural products

H Jaeschke, CD Williams, MR McGill, Y Xie… - Food and Chemical …, 2013 - Elsevier
Extracts from medicinal plants, many of which have been used for centuries, are increasingly
tested in models of hepatotoxicity. One of the most popular models to evaluate the …

Ethnopharmacology, phytochemistry and pharmacology of potent antibacterial medicinal plants from Africa

V Kuete - Advances in Botanical Research, 2023 - Elsevier
In this chapter, the traditional use, the phytochemical composition, and the pharmacological
activities of African medicinal plants displaying antibacterial effects were reported. We have …

[PDF][PDF] A review on the potential species of the zingiberaceae family with anti-viral efficacy towards enveloped viruses

AP Balaji, S Bhuvaneswari, LS Raj, G Bupesh… - J Pure Appl …, 2022 - researchgate.net
Natural products are a great wellspring of biodiversity for finding novel antivirals, exposing
new interactions between structure and operation and creating successful defensive or …

Inhibition of key enzymes linked to type 2 diabetes by compounds isolated from Aframomum melegueta fruit

A Mohammed, VA Gbonjubola… - Pharmaceutical …, 2017 - Taylor & Francis
Abstract Context: The use of Aframomum melegueta K. Schum.(Zingiberaceae) fruit for
treatment of diabetes has recently been established in Nigeria. However, compounds …

The role of spices in nutrition and health: a review of three popular spices used in Southern Nigeria

HA Ogbunugafor, CG Ugochukwu… - Food quality and …, 2017 - academic.oup.com
OBJECTIVES Spices are increasingly finding other useful roles in healthcare aside their
primary use as organoleptic enhancers in culinary. Several herbs and spices are currently …

Nephroprotective and anti-inflammatory potential of aqueous extract from Persea americana seeds against cadmium-induced nephrotoxicity in Wistar rats

OA Osukoya, BE Oyinloye, BO Ajiboye, KA Olokode… - Biometals, 2021 - Springer
Cadmium is a toxic metal and poses a high environmental risk to animals and humans,
alike. It is thus pertinent to search for medicinal plants in protecting against cadmium toxicity …

[HTML][HTML] Antioxidant extracts of African medicinal plants induce cell cycle arrest and differentiation in B16F10 melanoma cells

A Gismondi, L Canuti, S Impei… - International …, 2013 - spandidos-publications.com
African ethnomedicine is essentially based on the traditional use of vegetal extracts. Since
these natural drugs have shown health giving properties, in the present study we increased …

Anti-fatty liver effects of oils from Zingiber officinale and Curcuma longa on ethanol-induced fatty liver in rats

SO Nwozo, DA Osunmadewa, BE Oyinloye - Journal of Integrative …, 2014 - Elsevier
Objective The present study is aimed at evaluating the protective effects of oils from Zingiber
officinale (ginger) and Curcuma longa (turmeric) on acute ethanol-induced fatty liver in male …

Protective Effect of Aframomum melegueta phenolics Against CCl4-Induced Rat Hepatocytes Damage; Role of Apoptosis and Pro-inflammatory Cytokines inhibition

AM El-Halawany, RSE Dine, NS El Sayed, M Hattori - Scientific reports, 2014 - nature.com
Aframomum melegueta is a commonly used African spice. Through a hepatoprotective
bioassay-guided isolation, the chloroform fraction of A. melegueta seeds yielded one new …