5-HT receptors expressed throughout the human body are targets for established
therapeutics and various drugs in development. Their diversity of structure and function …

It is evident that in the last decade or so, a vast amount of new information has become
available concerning the various 5-HT receptor types and their characteristics. This derives …

The existence of an endogenous vasoconstrictor in blood serum (Stevens and Lee, 1984;
Brodie, 1900) and the presence in the gut of a substance that increases intestinal motility …

An overview of the behavioral data arising from the vast literature concerning the
involvement of 5-hydroxytryptamine (5-HT) neurotransmission in the regulation of anxiety is …

Abstract Serotonin (5‐hydroxytryptamine, 5‐HT) mediates a wide variety of physiological
functions by activating multiple receptors, and abnormalities of these receptor systems has …

Migraine patients have chronically low systemic 5‐HT, predisposing them to develop
migrainous headache once an attack has been initiated. Changes in platelet 5‐HT content …

The regional distribution and the pharmacology of the binding sites labelled with the novel 5-
hydroxytryptamine (serotonin) 5-HT 1B/1D selective radioligand serotonin-O-carboxy-methyl …

The serotonin 1D (5-HT1D) receptor is a pharmacologically defined binding site and
functional receptor site. Observed variations in the properties of 5-HT1D receptors in …

The abs~ m~ of selective anfagonisfs makes receptor characferizafion difficult, atzd largely
deperzdmt OIZ the use of agonists. Hozuever, there has been cousiderablc debate as to …

We describe the nucleic acid sequence encoding a human 5-hydroxytryptamine1D (5-
HT1D) serotonin receptor and some of the functional characteristics of the gene product. The …