Physiological and psychological stressors can exert wide-ranging effects on the human
brain and behavior. Research has improved understanding of how the sympatho-adreno …

Fear learning and regulation is a prominent model for describing the pathogenesis of
anxiety disorders and stress-related psychopathology. Fear expression can be modulated …

Recent models posit that bursts of locus ceruleus (LC) activity amplify neural gain such that
limited attention and encoding resources focus even more on prioritized mental …

Background Non-suicidal self-injury (NSSI) is a significant mental health problem among
adolescents. Research is needed to clarify the neurobiology of NSSI and identify candidate …

Extinction training is a form of inhibitory learning that allows an organism to associate a
previously aversive cue with a new, safe outcome. Extinction does not erase a fear …

Stress-induced changes in functional brain connectivity have been linked to the etiology of
stress-related disorders. Resting state functional connectivity (rsFC) is especially informative …

Oral contraceptives (OCs) are widely used yet understudied given their potential for public
health consequences. Emerging investigations scaling from single-subject, dense-sampling …

The amygdala is a hub of subcortical region that is crucial in a wide array of affective and
motivation-related behaviors. While early research contributed significantly to our …

In a dynamic environment, sources of threat or safety can unexpectedly change, requiring
the flexible updating of stimulus− outcome associations that promote adaptive behavior …

While the human brain has evolved extraordinary abilities to dominate nature, modern living
has paradoxically trapped it in a contemporary “cage” that stifles neuroplasticity. Within this …