Trace amines are endogenous compounds classically regarded as comprising β-
phenylethyalmine, p-tyramine, tryptamine, p-octopamine, and some of their metabolites …

Trace amine-associated receptor 1 (TAAR1) has emerged as a promising therapeutic target
for neuropsychiatric disorders due to its ability to modulate monoaminergic and …

The discovery in 2001 of a G protein-coupled receptor family, subsequently termed trace
amine-associated receptors (TAAR), triggered a resurgence of interest in so-called trace …

There are nine subfamilies of TAARs. They are predominantly intracellular, located in the
central nervous system and peripherally. They have a role in homeostasis and rheostasis …

The extensive use of amphetamines to treat attention deficit hyperactivity disorders in
children provides a compelling rationale for understanding the mechanisms of action of …

Trace amines, a group of amines expressed at the nanomolar level in the mammalian brain,
can modulate monoamine transmission. The discovery of and the functional research on the …

Abstract Trace Amine-Associated Receptor 1 (TAAR1) is a G protein-coupled receptor
expressed in the mammalian brain and known to influence subcortical monoaminergic …

Binge-eating disorder (BED) is the most prevalent eating disorder with estimates of 2–5% of
the general adult population. Nonetheless, its pathophysiology is poorly understood …

Compulsive, binge eating of highly palatable food constitutes a core feature of some forms of
obesity and eating disorders, as well as of the recently proposed disorder of food addiction …

Introduction: The trace amines, endogenous amines closely related to the biogenic amine
neurotransmitters, have been known to exert physiological and neurological effects for …