[HTML][HTML] Nutri-epigenetic effects of phenolic compounds from extra virgin olive oil: a systematic review

A del Saz-Lara, MCL de Las Hazas, F Visioli… - Advances in …, 2022 - Elsevier
Dietary components can induce epigenetic changes through DNA methylation, histone
modification, and regulation of microRNAs (miRNAs). Studies of diet-induced epigenetic …

Effects of hydroxytyrosol in endothelial functioning: a comprehensive review

U Vijakumaran, J Shanmugam, JW Heng, SS Azman… - Molecules, 2023 - mdpi.com
Pharmacologists have been emphasizing and applying plant and herbal-based treatments
in vascular diseases for decades now. Olives, for example, are a traditional symbol of the …

Procyanidin B2 regulates the Sirt1/Nrf2 signaling pathway to improve random‐pattern skin flap survival

Y Li, Y Zhu, F Hu, L Liu, G Shen, Q Tu - Phytotherapy Research, 2023 - Wiley Online Library
Random‐pattern skin flaps have been widely used in the reconstruction of damaged tissues.
Ischemia–reperfusion injury occurring in the distal regions of the flap is a common issue …

Nutraceutical activity in osteoarthritis biology: a focus on the nutrigenomic role

S D'Adamo, S Cetrullo, V Panichi, E Mariani… - Cells, 2020 - mdpi.com
Osteoarthritis (OA) is a disease associated to age or conditions that precipitate aging of
articular cartilage, a post-mitotic tissue that remains functional until the failure of major …

Oleanolic Acid Decreases IL‐1β‐Induced Activation of Fibroblast‐Like Synoviocytes via the SIRT3‐NF‐κB Axis in Osteoarthritis

J Bao, W Yan, K Xu, M Chen, Z Chen… - Oxidative Medicine …, 2020 - Wiley Online Library
Synovial inflammation is a major pathological feature of osteoarthritis (OA), which is a
chronic degenerative joint disease. Fibroblast‐like synoviocytes (FLS), localized in the …

Epigenetic modifications induced by olive oil and its phenolic compounds: A systematic review

R Fabiani, N Vella, P Rosignoli - Molecules, 2021 - mdpi.com
Many studies demonstrated that olive oil (especially extra virgin olive oil: EVOO) phenolic
compounds are bioactive molecules with anti-cancer, anti-inflammatory, anti-aging and …

[HTML][HTML] Nutritional epigenomics: bioactive dietary compounds in the epigenetic regulation of osteoarthritis

KM Villagrán-Andrade, C Núñez-Carro, FJ Blanco… - Pharmaceuticals, 2024 - mdpi.com
Nutritional epigenomics is exceptionally important because it describes the complex
interactions among food compounds and epigenome modifications. Phytonutrients or …

Is extra virgin olive oil an ally for women's and men's cardiovascular health?

F Franconi, I Campesi, A Romani - Cardiovascular …, 2020 - Wiley Online Library
Noncommunicable diseases are long‐lasting and slowly progressive and are the leading
causes of death and disability. They include cardiovascular diseases (CVD) and diabetes …

Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis: ANT3 is a potentially important novel …

X Du, Z Jiang, G Fang, R Liu, X Wen, Y Wu… - Bone & Joint …, 2023 - boneandjoint.org.uk
Aims This study aimed to investigate the role and mechanism of meniscal cell lysate (MCL)
in fibroblast-like synoviocytes (FLSs) and osteoarthritis (OA). Methods Meniscus and …

[HTML][HTML] Hydroxytyrosol decreases EDNRA expression through epigenetic modification in colorectal cancer cells

A del Saz-Lara, H Boughanem… - Pharmacological …, 2023 - Elsevier
The Mediterranean diet (MD) is one of the healthiest ones and is associated with a lower
incidence of cardiovascular and cerebrovascular diseases as well as cancer. Extra virgin …