Cyclodextrins and their derivatives as drug stability modifiers

V Aiassa, C Garnero, A Zoppi, MR Longhi - Pharmaceuticals, 2023 - mdpi.com
Cyclodextrins (CDs) are cyclic oligosaccharides that contain a relatively hydrophobic central
cavity and a hydrophilic outer surface. They are widely used to form non-covalent inclusion …

Sunscreens containing cyclodextrin inclusion complexes for enhanced efficiency: A strategy for skin cancer prevention

L Dahabra, G Broadberry, A Le Gresley, M Najlah… - Molecules, 2021 - mdpi.com
Unprotected exposure of skin to solar ultraviolet radiation (UVR) may damage the DNA of
skin cells and can lead to skin cancer. Sunscreens are topical formulations used to protect …

[HTML][HTML] Quercetin, rutin and quercetin-rutin incorporated hydroxypropyl β-cyclodextrin inclusion complexes

E Başaran, AA Öztürk, B Şenel, M Demirel… - European journal of …, 2022 - Elsevier
Quercetin (Q) and rutin (R) are well known and most studied flavonoids due to their activities
in reduction of inflammation, oxidative damage, platelet aggregation and inhibition of cancer …

Rutin nanocrystals with enhanced anti-inflammatory activity: Preparation and ex vivo/in vivo evaluation in an inflammatory rat model

AS Hassan, GM Soliman - Pharmaceutics, 2022 - mdpi.com
Rutin is a polyphenolic flavonoid with an interestingly wide therapeutic spectrum. However,
its clinical benefits are limited by its poor aqueous solubility and low bioavailability. In an …

Preparation, characterization and molecular dynamics simulation of rutin–cyclodextrin inclusion complexes

C Chang, M Song, M Ma, J Song, F Cao, Q Qin - Molecules, 2023 - mdpi.com
Rutin is a natural flavonoid that carries out a variety of biological activities, but its application
in medicine and food is limited by its water solubility. One of the classical methods used to …

The mechanism of bensulfuron-methyl complexation with β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin and effect on soil adsorption and bio-activity

Q Geng, T Li, X Wang, W Chu, M Cai, J Xie, H Ni - Scientific Reports, 2019 - nature.com
In this work, the inclusion complexes of hydrophobic herbicide bensulfuron-methyl (BSM)
with β-cyclodextrin (β-CD) and (2-hydroxypropyl)-β-CD (2-HP-β-CD) were prepared and …

Synthesis, characterization, antioxidant activity of Quercetin, Rutin and Quercetin-Rutin incorporated β-cyclodextrin inclusion complexes and determination of their …

AA Öztürk, E Başaran, B Şenel, M Demirel… - Journal of Molecular …, 2023 - Elsevier
Quercetin (Q) and rutin (R) are plant-originated polyphenolic flavonoids with considerably
strong antioxidant and anticancer activity. Despite their potentials, low water solubility …

Administration routes for nano drugs and characterization of nano drug loading

V Nikolić, S Ilić-Stojanović, S Petrović, A Tačić… - … and biology of …, 2019 - Elsevier
This chapter summarizes the types of nano drugs, their synthesis, formulation,
characterization, and applications, with the most important administration routes. To achieve …

Preparation, characterization and antimicrobial activity of inclusion complex of biochanin A with (2-hydroxypropyl)-β-cyclodextrin

IL Nikolic, IM Savic, MM Popsavin… - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives An inclusion complex of biochanin A (BCA) with (2-hydroxypropyl)-β-cyclodextrin
(HP-β-CD) was prepared in the ethanol solution to improve its water solubility. Methods …

Physico-chemical and pharmaco-technical characterization of inclusion complexes formed by rutoside with β-cyclodextrin and hydroxypropyl-β-cyclodextrin used to …

T Balaci, B Velescu, O Karampelas, AM Musuc… - Processes, 2020 - mdpi.com
The aim of our study was to obtain rutoside (RUT) inclusion complexes in β-cyclodextrin (β-
CD) and in hydroxypropyl-β-cyclodextrin (HP-β-CD), in a 1: 1 molar ratio, using the …