Cyclodextrins and their derivatives as drug stability modifiers
Cyclodextrins (CDs) are cyclic oligosaccharides that contain a relatively hydrophobic central
cavity and a hydrophilic outer surface. They are widely used to form non-covalent inclusion …
cavity and a hydrophilic outer surface. They are widely used to form non-covalent inclusion …
Sunscreens containing cyclodextrin inclusion complexes for enhanced efficiency: A strategy for skin cancer prevention
L Dahabra, G Broadberry, A Le Gresley, M Najlah… - Molecules, 2021 - mdpi.com
Unprotected exposure of skin to solar ultraviolet radiation (UVR) may damage the DNA of
skin cells and can lead to skin cancer. Sunscreens are topical formulations used to protect …
skin cells and can lead to skin cancer. Sunscreens are topical formulations used to protect …
[HTML][HTML] Quercetin, rutin and quercetin-rutin incorporated hydroxypropyl β-cyclodextrin inclusion complexes
Quercetin (Q) and rutin (R) are well known and most studied flavonoids due to their activities
in reduction of inflammation, oxidative damage, platelet aggregation and inhibition of cancer …
in reduction of inflammation, oxidative damage, platelet aggregation and inhibition of cancer …
Rutin nanocrystals with enhanced anti-inflammatory activity: Preparation and ex vivo/in vivo evaluation in an inflammatory rat model
AS Hassan, GM Soliman - Pharmaceutics, 2022 - mdpi.com
Rutin is a polyphenolic flavonoid with an interestingly wide therapeutic spectrum. However,
its clinical benefits are limited by its poor aqueous solubility and low bioavailability. In an …
its clinical benefits are limited by its poor aqueous solubility and low bioavailability. In an …
Preparation, characterization and molecular dynamics simulation of rutin–cyclodextrin inclusion complexes
C Chang, M Song, M Ma, J Song, F Cao, Q Qin - Molecules, 2023 - mdpi.com
Rutin is a natural flavonoid that carries out a variety of biological activities, but its application
in medicine and food is limited by its water solubility. One of the classical methods used to …
in medicine and food is limited by its water solubility. One of the classical methods used to …
The mechanism of bensulfuron-methyl complexation with β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin and effect on soil adsorption and bio-activity
Q Geng, T Li, X Wang, W Chu, M Cai, J Xie, H Ni - Scientific Reports, 2019 - nature.com
In this work, the inclusion complexes of hydrophobic herbicide bensulfuron-methyl (BSM)
with β-cyclodextrin (β-CD) and (2-hydroxypropyl)-β-CD (2-HP-β-CD) were prepared and …
with β-cyclodextrin (β-CD) and (2-hydroxypropyl)-β-CD (2-HP-β-CD) were prepared and …
Synthesis, characterization, antioxidant activity of Quercetin, Rutin and Quercetin-Rutin incorporated β-cyclodextrin inclusion complexes and determination of their …
Quercetin (Q) and rutin (R) are plant-originated polyphenolic flavonoids with considerably
strong antioxidant and anticancer activity. Despite their potentials, low water solubility …
strong antioxidant and anticancer activity. Despite their potentials, low water solubility …
Administration routes for nano drugs and characterization of nano drug loading
V Nikolić, S Ilić-Stojanović, S Petrović, A Tačić… - … and biology of …, 2019 - Elsevier
This chapter summarizes the types of nano drugs, their synthesis, formulation,
characterization, and applications, with the most important administration routes. To achieve …
characterization, and applications, with the most important administration routes. To achieve …
Preparation, characterization and antimicrobial activity of inclusion complex of biochanin A with (2-hydroxypropyl)-β-cyclodextrin
IL Nikolic, IM Savic, MM Popsavin… - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives An inclusion complex of biochanin A (BCA) with (2-hydroxypropyl)-β-cyclodextrin
(HP-β-CD) was prepared in the ethanol solution to improve its water solubility. Methods …
(HP-β-CD) was prepared in the ethanol solution to improve its water solubility. Methods …
Physico-chemical and pharmaco-technical characterization of inclusion complexes formed by rutoside with β-cyclodextrin and hydroxypropyl-β-cyclodextrin used to …
The aim of our study was to obtain rutoside (RUT) inclusion complexes in β-cyclodextrin (β-
CD) and in hydroxypropyl-β-cyclodextrin (HP-β-CD), in a 1: 1 molar ratio, using the …
CD) and in hydroxypropyl-β-cyclodextrin (HP-β-CD), in a 1: 1 molar ratio, using the …