[HTML][HTML] The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer's disease pathology: From antioxidant to epigenetic therapy

C Grinán-Ferré, A Bellver-Sanchis, V Izquierdo… - Ageing Research …, 2021 - Elsevier
While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

[HTML][HTML] A review of resveratrol as a potent chemoprotective and synergistic agent in cancer chemotherapy

Q Xiao, W Zhu, W Feng, SS Lee, AW Leung… - Frontiers in …, 2019 - frontiersin.org
Background: Cancer has become a major disease endangering human health around the
world. Conventional chemotherapy suffers from many side effects including pain …

Aging, lifestyle and dementia

D Wahl, SM Solon-Biet, VC Cogger, L Fontana… - Neurobiology of …, 2019 - Elsevier
Aging is the greatest risk factor for most diseases including cancer, cardiovascular disorders,
and neurodegenerative disease. There is emerging evidence that interventions that improve …

[HTML][HTML] Chitosan-tripolyphosphate nanoparticles designed to encapsulate polyphenolic compounds for biomedical and pharmaceutical applications− A review

MC Di Santo, CL D'Antoni, APD Rubio, A Alaimo… - Biomedicine & …, 2021 - Elsevier
Plant-based polyphenols are natural compounds, present in fruits and vegetables. During
recent years, polyphenols have gained special attention due to their nutraceutical and …

The roles of flavonols/flavonoids in neurodegeneration and neuroinflammation

Z Calis, R Mogulkoc, AK Baltaci - Mini Reviews in Medicinal …, 2020 - ingentaconnect.com
The inflammatory process in the human body is a physiological response involving many
cellular types and mediators. It results in scar formation to separate the damaged area from …

[HTML][HTML] Phenolic compounds characteristic of the mediterranean diet in mitigating microglia-mediated neuroinflammation

R Hornedo-Ortega, AB Cerezo… - Frontiers in Cellular …, 2018 - frontiersin.org
Neuroinflammation is a pathological feature of quite a number of Central Nervous System
diseases such as Alzheimer and Parkinson's disease among others. The hallmark of brain …

[HTML][HTML] Phytochemicals as regulators of genes involved in synucleinopathies

A Surguchov, L Bernal, AA Surguchev - Biomolecules, 2021 - mdpi.com
Synucleinopathies are a group of neurodegenerative diseases characterized by the
accumulation of α-synuclein aggregates in neurons, nerve fibers or glial cells. Three main …

Resveratrol encapsulation in high molecular weight chitosan-based nanogels for applications in ocular treatments: Impact on human ARPE-19 culture cells

FS Buosi, A Alaimo, MC Di Santo, F Elias… - International Journal of …, 2020 - Elsevier
Oxidative stress and inflammation play a pivotal role in ocular diseases. Resveratrol (RSV)
is a natural bioactive that has recently attracted attention due to it potent antioxidant and anti …

[HTML][HTML] Impact of gut microbiota in brain ageing: polyphenols as beneficial modulators

F Sarubbo, D Moranta, S Tejada, M Jiménez… - Antioxidants, 2023 - mdpi.com
Brain ageing is a complex physiological process that includes several mechanisms. It is
characterized by neuronal/glial dysfunction, alterations in brain vasculature and barriers …

Targeting the central nervous system: From synthetic nanoparticles to extracellular vesicles—Focus on Alzheimer's and Parkinson's disease

S Hernando, E Santos‐Vizcaíno… - Wiley …, 2023 - Wiley Online Library
Neurodegenerative diseases (NDs) such as Alzheimer's disease (AD) and Parkinson's
disease (PD) are an accelerating global health problem as life expectancy rises worldwide …